Antifungal Activity of Chitosan Nanoparticles and Correlation with Their Physical Properties
المؤلفون المشاركون
Ing, Ling Yien
Zin, Noraziah Mohamad
Sarwar, Atif
Katas, Haliza
المصدر
International Journal of Biomaterials
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-07-08
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
The need of natural antimicrobials is paramount to avoid harmful synthetic chemicals.
The study aimed to determine the antifungal activity of natural compound chitosan and its nanoparticles forms against Candida albicans, Fusarium solani and Aspergillus niger.
Chitosan nanoparticles were prepared from low (LMW), high molecular weight (HMW) chitosan and its derivative, trimethyl chitosan (TMC).
Particle size was increased when chitosan/TMC concentration was increased from 1 to 3 mg/mL.
Their zeta potential ranged from +22 to +55 mV.
Chitosan nanoparticles prepared from different concentrations of LMW and HMW were also found to serve a better inhibitory activity against C.
albicans (MICLMW=0.25–0.86 mg/mL and MICHMW=0.6–1.0 mg/mL) and F.
solani (MICLMW=0.86–1.2 mg/mL and MICHMW=0.5–1.2 mg/mL) compared to the solution form (MIC=3 mg/mL for both MWs and species).
This inhibitory effect was also influenced by particle size and zeta potential of chitosan nanoparticles.
Besides, Aspergillus niger was found to be resistant to chitosan nanoparticles except for nanoparticles prepared from higher concentrations of HMW.
Antifungal activity of nanoparticles prepared from TMC was negligible.
The parent compound therefore could be formulated and applied as a natural antifungal agent into nanoparticles form to enhance its antifungal activity.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ing, Ling Yien& Zin, Noraziah Mohamad& Sarwar, Atif& Katas, Haliza. 2012. Antifungal Activity of Chitosan Nanoparticles and Correlation with Their Physical Properties. International Journal of Biomaterials،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-486775
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ing, Ling Yien…[et al.]. Antifungal Activity of Chitosan Nanoparticles and Correlation with Their Physical Properties. International Journal of Biomaterials No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-486775
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ing, Ling Yien& Zin, Noraziah Mohamad& Sarwar, Atif& Katas, Haliza. Antifungal Activity of Chitosan Nanoparticles and Correlation with Their Physical Properties. International Journal of Biomaterials. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-486775
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-486775
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر