Natural Compounds as Regulators of the Cancer Cell Metabolism
المؤلفون المشاركون
Cerella, Claudia
Dicato, Mario
Diederich, Marc
Radogna, Flavia
المصدر
International Journal of Cell Biology
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-16، 16ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-05-16
دولة النشر
مصر
عدد الصفحات
16
التخصصات الرئيسية
الملخص EN
Even though altered metabolism is an “old” physiological mechanism, only recently its targeting became a therapeutically interesting strategy and by now it is considered an emerging hallmark of cancer.
Nevertheless, a very poor number of compounds are under investigation as potential modulators of cell metabolism.
Candidate agents should display selectivity of action towards cancer cells without side effects.
This ideal favorable profile would perfectly overlap the requisites of new anticancer therapies and chemopreventive strategies as well.
Nature represents a still largely unexplored source of bioactive molecules with a therapeutic potential.
Many of these compounds have already been characterized for their multiple anticancer activities.
Many of them are absorbed with the diet and therefore possess a known profile in terms of tolerability and bioavailability compared to newly synthetized chemical compounds.
The discovery of important cross-talks between mediators of the most therapeutically targeted aberrancies in cancer (i.e., cell proliferation, survival, and migration) and the metabolic machinery allows to predict the possibility that many anticancer activities ascribed to a number of natural compounds may be due, in part, to their ability of modulating metabolic pathways.
In this review, we attempt an overview of what is currently known about the potential of natural compounds as modulators of cancer cell metabolism.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Cerella, Claudia& Radogna, Flavia& Dicato, Mario& Diederich, Marc. 2013. Natural Compounds as Regulators of the Cancer Cell Metabolism. International Journal of Cell Biology،Vol. 2013, no. 2013, pp.1-16.
https://search.emarefa.net/detail/BIM-487333
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Cerella, Claudia…[et al.]. Natural Compounds as Regulators of the Cancer Cell Metabolism. International Journal of Cell Biology No. 2013 (2013), pp.1-16.
https://search.emarefa.net/detail/BIM-487333
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Cerella, Claudia& Radogna, Flavia& Dicato, Mario& Diederich, Marc. Natural Compounds as Regulators of the Cancer Cell Metabolism. International Journal of Cell Biology. 2013. Vol. 2013, no. 2013, pp.1-16.
https://search.emarefa.net/detail/BIM-487333
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-487333
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر