Significance of Soluble Lectin-Like Oxidized LDL Receptor-1 Levels in Systemic and Coronary Circulation in Acute Coronary Syndrome
المؤلفون المشاركون
Nakazato, Kazuhiko
Sawamura, Tatsuya
Misaka, Tomofumi
Saitoh, Shu-ichi
Sakamoto, Nobuo
Sugimoto, Koichi
Suzuki, Satoshi
Takeishi, Yasuchika
Ishibashi, Toshiyuki
Yamaki, Takayoshi
Kunii, Hiroyuki
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-05-07
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
Soluble lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) level is a novel biomarker for diagnosis of acute coronary syndrome (ACS); however, this level in the coronary circulation has yet to be examined.
Methods.
Twenty-seven consecutive patients with ACS and 40 patients with effort angina pectoris (EAP) undergoing percutaneous coronary intervention (PCI) had levels of soluble LOX-1 and LOX-1 index measured in paired blood samples from aorta (Ao) and coronary sinus (CS) just prior to the PCI.
Results.
We found positive correlations between soluble LOX-1 levels in the Ao and CS in both ACS and EAP patients (P<0.01, for both).
The soluble LOX-1 levels in the Ao and CS were higher in ACS than in EAP patients (P<0.01, for both).
The levels of soluble LOX-1 and LOX-1 index of the CS were significantly greater than those of the Ao in both ACS and EAP patients (P<0.01, for both).
Receiver operating characteristic curves for ACS detection demonstrated high sensitivity and specificity for the soluble LOX-1 and LOX-1 index with no differences between the Ao and CS.
Conclusions.
The present study showed that circulating soluble LOX-1 originates from coronary circulation and soluble LOX-1 and LOX-1 index are useful biomarkers for ACS.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Misaka, Tomofumi& Suzuki, Satoshi& Sakamoto, Nobuo& Yamaki, Takayoshi& Sugimoto, Koichi& Kunii, Hiroyuki…[et al.]. 2014. Significance of Soluble Lectin-Like Oxidized LDL Receptor-1 Levels in Systemic and Coronary Circulation in Acute Coronary Syndrome. BioMed Research International،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-488102
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Misaka, Tomofumi…[et al.]. Significance of Soluble Lectin-Like Oxidized LDL Receptor-1 Levels in Systemic and Coronary Circulation in Acute Coronary Syndrome. BioMed Research International No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-488102
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Misaka, Tomofumi& Suzuki, Satoshi& Sakamoto, Nobuo& Yamaki, Takayoshi& Sugimoto, Koichi& Kunii, Hiroyuki…[et al.]. Significance of Soluble Lectin-Like Oxidized LDL Receptor-1 Levels in Systemic and Coronary Circulation in Acute Coronary Syndrome. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-488102
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-488102
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر