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Mycobacterial Etiology of Pulmonary Tuberculosis and Association with HIV Infection and Multidrug Resistance in Northern Nigeria
المؤلفون المشاركون
El-Kamary, Samer S.
Blattner, William
Mosunmola, Iwakun
Obasanya, Joshua
Hungerford, Laura
Brown, Clayton
Ezati, Nicholas
Tracy, Kathleen J.
Abimiku, Alash'le
Aliyu, Gambo
المصدر
Tuberculosis Research and Treatment
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-07-16
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Objective.
Data on pulmonary tuberculosis (TB) caused by Mycobacterium tuberculosis (MTB) complex in Nigeria are limited.
We investigated species of MTB complex in TB cases from northern Nigeria.
Methods.
New TB suspects were enrolled, screened for HIV and their sputum samples were cultured after routine microscopy.
Genotypes MTBC and MTBDRplus were used to characterize the MTB complex species and their resistance to isoniazid and rifampicin.
Results.
Of the 1,603 patients enrolled, 375 (23%) had MTB complex infection: 354 (94.4%) had Mycobacterium tuberculosis; 20 (5.3%) had Mycobacterium africanum; and one had Mycobacterium bovis (0.3%).
Cases were more likely to be male (AOR = 1.87, 95% CI : 1.42–2.46; P≤0.001), young (AOR = 2.03, 95% CI : 1.56–2.65; P≤0.001) and have HIV (AOR = 1.43, 95% CI : 1.06–1.92; P=0.032).
In 23 patients (6.1%), the mycobacterium was resistant to at least one drug, and these cases were more likely to have HIV and prior TB treatment (AOR = 3.62, 95% CI : 1.51–8.84; P=0.004; AOR : 4.43; 95% CI : 1.71–11.45 P=0.002 resp.), compared to cases without any resistance.
Conclusion.
Mycobacterium tuberculosis remained the predominant specie in TB in this setting followed by Mycobacterium africanum while Mycobacterium bovis was rare.
The association of TB drug resistance with HIV has implications for TB treatment.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Aliyu, Gambo& El-Kamary, Samer S.& Abimiku, Alash'le& Ezati, Nicholas& Mosunmola, Iwakun& Hungerford, Laura…[et al.]. 2013. Mycobacterial Etiology of Pulmonary Tuberculosis and Association with HIV Infection and Multidrug Resistance in Northern Nigeria. Tuberculosis Research and Treatment،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-488230
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Aliyu, Gambo…[et al.]. Mycobacterial Etiology of Pulmonary Tuberculosis and Association with HIV Infection and Multidrug Resistance in Northern Nigeria. Tuberculosis Research and Treatment No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-488230
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Aliyu, Gambo& El-Kamary, Samer S.& Abimiku, Alash'le& Ezati, Nicholas& Mosunmola, Iwakun& Hungerford, Laura…[et al.]. Mycobacterial Etiology of Pulmonary Tuberculosis and Association with HIV Infection and Multidrug Resistance in Northern Nigeria. Tuberculosis Research and Treatment. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-488230
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-488230
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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