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Premature Coronary Artery Disease and Familial Hypercholesterolemia : Need for Early Diagnosis and Cascade Screening in the Indian Population
المؤلفون المشاركون
Khan, Bobby Varkey
Verma, I. C.
Setia, N.
Arora, Anjali
المصدر
Cardiology Research and Practice
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-10-27
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
Cardiovascular disease (CVD) is the leading cause of death in India, accounting for 28% of mortality.
The average age of onset of CVD is younger (below 55 years) among Indians than in other populations.
This may be due to bad lifestyle, genetic factors, or both.
Hypertension, smoking, diabetes, and physical inactivity have been identified as modifiable risk factors for heart disease.
Hypercholesterolemia is the most common and treatable cause of heart disease.
Genetic factors that lead to hypercholesterolemia have not been fully studied in India.
Familial Hypercholesterolemia results from mutations in the LDL receptor, ApoB, PCSK9, and ApoE genes.
There is an urgent need to screen subjects with premature CAD and their relatives in India for the presence of FH, identify the mutations that lead to high cholesterol, and carry out cascade screening in the at-risk relatives.
Those harbouring mutations in the above genes can be treated to lower the cholesterol levels, prevent early CVD, and avoid death.
A programme based on these lines has been initiated in Delhi.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Setia, N.& Verma, I. C.& Khan, Bobby Varkey& Arora, Anjali. 2011. Premature Coronary Artery Disease and Familial Hypercholesterolemia : Need for Early Diagnosis and Cascade Screening in the Indian Population. Cardiology Research and Practice،Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-488910
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Setia, N.…[et al.]. Premature Coronary Artery Disease and Familial Hypercholesterolemia : Need for Early Diagnosis and Cascade Screening in the Indian Population. Cardiology Research and Practice No. 2012 (2012), pp.1-4.
https://search.emarefa.net/detail/BIM-488910
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Setia, N.& Verma, I. C.& Khan, Bobby Varkey& Arora, Anjali. Premature Coronary Artery Disease and Familial Hypercholesterolemia : Need for Early Diagnosis and Cascade Screening in the Indian Population. Cardiology Research and Practice. 2011. Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-488910
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-488910
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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