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New Insight into Adiponectin Role in Obesity and Obesity-Related Diseases
المؤلفون المشاركون
Monaco, Maria Ludovica
Bianco, Andrea
Mazzarella, Gennaro
Daniele, Aurora
Costagliola, Ciro
Nigro, Ersilia
Palmieri, Alessia
Scudiero, Olga
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-14، 14ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-07-07
دولة النشر
مصر
عدد الصفحات
14
التخصصات الرئيسية
الملخص EN
Obesity is a major health problem strongly increasing the risk for various severe related complications such as metabolic syndrome, cardiovascular diseases, respiratory disorders, diabetic retinopathy, and cancer.
Adipose tissue is an endocrine organ that produces biologically active molecules defined “adipocytokines,” protein hormones with pleiotropic functions involved in the regulation of energy metabolism as well as in appetite, insulin sensitivity, inflammation, atherosclerosis, cell proliferation, and so forth.
In obesity, fat accumulation causes dysregulation of adipokine production that strongly contributes to the onset of obesity-related diseases.
Several advances have been made in the treatment and prevention of obesity but current medical therapies are often unsuccessful even in compliant patients.
Among the adipokines, adiponectin shows protective activity in various processes such as energy metabolism, inflammation, and cell proliferation.
In this review, we will focus on the current knowledge regarding the protective properties of adiponectin and its receptors, AdipoRs (“adiponectin system”), on metabolic complications in obesity and obesity-related diseases.
Adiponectin, exhibiting antihyperglycemic, antiatherogenic, and anti-inflammatory properties, could have important clinical benefits in terms of development of therapies for the prevention and/or for the treatment of obesity and obesity-related diseases.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Nigro, Ersilia& Scudiero, Olga& Monaco, Maria Ludovica& Palmieri, Alessia& Mazzarella, Gennaro& Costagliola, Ciro…[et al.]. 2014. New Insight into Adiponectin Role in Obesity and Obesity-Related Diseases. BioMed Research International،Vol. 2014, no. 2014, pp.1-14.
https://search.emarefa.net/detail/BIM-488942
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Nigro, Ersilia…[et al.]. New Insight into Adiponectin Role in Obesity and Obesity-Related Diseases. BioMed Research International No. 2014 (2014), pp.1-14.
https://search.emarefa.net/detail/BIM-488942
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Nigro, Ersilia& Scudiero, Olga& Monaco, Maria Ludovica& Palmieri, Alessia& Mazzarella, Gennaro& Costagliola, Ciro…[et al.]. New Insight into Adiponectin Role in Obesity and Obesity-Related Diseases. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-14.
https://search.emarefa.net/detail/BIM-488942
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-488942
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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