Use of Immunohistochemistry Techniques in Patients Exposed to Sulphur Mustard Gas
المؤلفون المشاركون
Bahadori, Moslem
Ghanei, Mostafa
Shamsaei, Hassan
Chilosi, Marco
Tazelaar, Henry D.
Amini Harandi, Asghar
Motiei-Langroudi, Rouzbeh
Mohammad Hosseini Akbari, Hassan
المصدر
Pathology Research International
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-07-06
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
We performed a pathologic study with further using an immunohistochemical technique (using anti-p63 and anti-CK5) on tissues obtained by open lung biopsy from 18 patients with previous exposure to sulphur mustard (SM) as case group and 8 unexposed patients (control group).
The most frequent pathologic diagnosis was constrictive bronchiolitis (44.4%), followed by respiratory (22.2%) and chronic cellular bronchiolitis (16.7%) in the case group, and hypersensitivity bronchiolitis (50%) in the control group.
The pathologic diagnoses were significantly different in the case and control groups (P=0.042).
In slides stained by anti-p63 and anti-CK5, the percent of stained cells and the mean number of epithelial cells were lower in the case group in comparison to the control group.
This difference was significant for the mean number of cells stained by anti-CK5 (P=0.042).
Furthermore, there was a significant correlation between pathologic diagnosis and total number of cells and mean number of cells stained with anti-p63 and anti-CK5 (P value = 0.002, <0.001, 0.044).
These results suggest that constrictive bronchiolitis may be the major pathologic consequence of exposure to SM.
Moreover, decrease of p63 in respiratory tissues affected by SM may suggest the lack of regenerative capacity in these patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ghanei, Mostafa& Chilosi, Marco& Mohammad Hosseini Akbari, Hassan& Motiei-Langroudi, Rouzbeh& Amini Harandi, Asghar& Shamsaei, Hassan…[et al.]. 2011. Use of Immunohistochemistry Techniques in Patients Exposed to Sulphur Mustard Gas. Pathology Research International،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-489028
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ghanei, Mostafa…[et al.]. Use of Immunohistochemistry Techniques in Patients Exposed to Sulphur Mustard Gas. Pathology Research International No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-489028
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ghanei, Mostafa& Chilosi, Marco& Mohammad Hosseini Akbari, Hassan& Motiei-Langroudi, Rouzbeh& Amini Harandi, Asghar& Shamsaei, Hassan…[et al.]. Use of Immunohistochemistry Techniques in Patients Exposed to Sulphur Mustard Gas. Pathology Research International. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-489028
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-489028
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر