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In Vitro and In Vivo Activities of Essential Oil from the Seed of Anethum graveolens L. against Candida spp.
المؤلفون المشاركون
Zeng, Jingsi
Mao, Yehong
Wang, Youwei
Tian, Jun
Zeng, Hong
Zheng, Yuechen
Ban, Xiaoquan
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-05-11
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
The essential oil produced from the seed of Anethum graveolens L.
(Umbelliferae) was tested in vitro and in vivo anti-Candida activity.
The microbroth dilution method was used in the minimal inhibitory concentration (MIC), according to M27-A3 of the guidelines of the Clinical and Laboratory Standard Institute (CLSI).
And then, efficacy evaluation of essential oil in the prophylaxis and treatment of experimental vaginal candidiasis was performed in immunosuppressed mice.
The anti-Candida activity was analyzed by microbiological and histological techniques and was compared with that of fluconazole (FCZ).
The results showed essential oil was active in vitro against all tested strains, with MICs ranging from 0.312 μL/mL (for C.
tropicalis, C.
parapsilosis, and C.
krusei) to 0.625 μL/mL (for 6 isolated C.
albicans strains).
Essential oil (2% v/v) was highly efficacious in accelerating C.
albicans 09-1555 clearance from experimentally infected mice vagina by prophylaxis and therapeutic treatments.
In both therapeutic efficacy and prophylaxis studies, the histological findings confirmed the microbiological results.
The experimental results revealed that the tested essential oil is effective against vulvovaginal candidiasis in immunosuppressed mice.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zeng, Hong& Tian, Jun& Zheng, Yuechen& Ban, Xiaoquan& Zeng, Jingsi& Mao, Yehong…[et al.]. 2011. In Vitro and In Vivo Activities of Essential Oil from the Seed of Anethum graveolens L. against Candida spp.. Evidence-Based Complementary and Alternative Medicine،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-489047
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zeng, Hong…[et al.]. In Vitro and In Vivo Activities of Essential Oil from the Seed of Anethum graveolens L. against Candida spp.. Evidence-Based Complementary and Alternative Medicine No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-489047
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zeng, Hong& Tian, Jun& Zheng, Yuechen& Ban, Xiaoquan& Zeng, Jingsi& Mao, Yehong…[et al.]. In Vitro and In Vivo Activities of Essential Oil from the Seed of Anethum graveolens L. against Candida spp.. Evidence-Based Complementary and Alternative Medicine. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-489047
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-489047
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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