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Characterization of the Antidiabetic Role of Parkinsonia aculeata (Caesalpineaceae)
المؤلفون المشاركون
Araújo, Tiago Gomes
Leite, Ana Catarina Rezende
Lima, Vera Lúcia de Menezes
Maia, Maria Bernadete de Sousa
Carvalho, Bruno de Melo
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2010-09-19
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
This paper reports the characterization of the antidiabetic role of a hydroethanolic extract from Parkinsonia aerial parts (HEPA), in normal and alloxan-induced diabetic rats, treated with HEPA (125 and 250 mg/kg; p.o.).
Oral glucose tolerance test, acute oral toxicity test and preliminary phytochemical analyses were performed.
The diabetic rats treated with HEPA showed a significant reduction in serum and urinary glucose, urinary urea and triglyceride levels, as compared to the diabetic untreated group.
However, in the normal treated groups, a significant reduction was found only in serum triglyceride levels.
In all treated diabetic groups, an improvement in hepatic glycogen was observed, as well as a decrease in liquid intake and urinary volume, and an enhancement in the weight of skeletal muscles (soleus and extensor digitorum longus), kidneys and epididymal adipose tissue.
Nevertheless, body and liver weights were ameliorated only in the diabetic group treated with HEPA (250 mg/kg).
Moreover, oral glucose tolerance was higher in animals treated with HEPA, while results also showed that HEPA could be considered toxicologically safe.
Phytochemical analysis revealed the presence of tanins, flavonoids and steroids in HEPA.
In conclusion, P.
aculeata presents an antidiabetic activity and other beneficial effects that ameliorate diabetes and associated complications.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Leite, Ana Catarina Rezende& Araújo, Tiago Gomes& Carvalho, Bruno de Melo& Maia, Maria Bernadete de Sousa& Lima, Vera Lúcia de Menezes. 2010. Characterization of the Antidiabetic Role of Parkinsonia aculeata (Caesalpineaceae). Evidence-Based Complementary and Alternative Medicine،Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-491000
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Leite, Ana Catarina Rezende…[et al.]. Characterization of the Antidiabetic Role of Parkinsonia aculeata (Caesalpineaceae). Evidence-Based Complementary and Alternative Medicine No. 2011 (2011), pp.1-9.
https://search.emarefa.net/detail/BIM-491000
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Leite, Ana Catarina Rezende& Araújo, Tiago Gomes& Carvalho, Bruno de Melo& Maia, Maria Bernadete de Sousa& Lima, Vera Lúcia de Menezes. Characterization of the Antidiabetic Role of Parkinsonia aculeata (Caesalpineaceae). Evidence-Based Complementary and Alternative Medicine. 2010. Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-491000
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-491000
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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