Newborn Screening for Sickle Cell Disease : Technical and Legal Aspects of a German Pilot Study with 38,220 Participants
المؤلفون المشاركون
Brose, Annemarie
Frömmel, Claudia
Blankenstein, Oliver
Klein, Jeannette
Lobitz, Stephan
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-07-23
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Sickle cell disease (SCD) does not occur in the indigenous German population, but with the increasing number of immigrants from countries at high risk for hemoglobinopathies, the question emerges whether or not a newborn screening program (NBS) for SCD disease should be initiated in Germany anyhow.
We have recently shown that in Berlin, a city with a very large immigrant population, the incidence of SCD is considerable, but our findings are insufficient to make a decision for the country as a whole.
In this paper we will show that a large body of epidemiological data can be generated in a relatively short period of time, with a very high degree of precision and at relatively little expense—a result that might motivate other working groups to start such a pilot project locally.
We examined previously collected dried blood cards that were up to six months old, using high performance liquid chromatography (HPLC) as first method and capillary electrophoresis (CE) as second method.
A single, part-time laboratory technician processed 38,220 samples in a period of 162 working days.
The total costs per sample including all incidentals (as well as labor costs) were EUR 1.44.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Frömmel, Claudia& Brose, Annemarie& Klein, Jeannette& Blankenstein, Oliver& Lobitz, Stephan. 2014. Newborn Screening for Sickle Cell Disease : Technical and Legal Aspects of a German Pilot Study with 38,220 Participants. BioMed Research International،Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-491303
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Frömmel, Claudia…[et al.]. Newborn Screening for Sickle Cell Disease : Technical and Legal Aspects of a German Pilot Study with 38,220 Participants. BioMed Research International No. 2014 (2014), pp.1-10.
https://search.emarefa.net/detail/BIM-491303
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Frömmel, Claudia& Brose, Annemarie& Klein, Jeannette& Blankenstein, Oliver& Lobitz, Stephan. Newborn Screening for Sickle Cell Disease : Technical and Legal Aspects of a German Pilot Study with 38,220 Participants. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-491303
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-491303
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر