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Synthesis, Characterization and In Vitro Antibacterial Studies of Organotin(IV) Complexes with 2-Hydroxyacetophenone-2-methylphenylthiosemicarbazone (H2dampt)
المؤلفون المشاركون
Salam, M. A.
Ahmad, Fasihuddin Badruddin
Sam, Norrihan
Saha, Ramkrishna
Affan, M. A.
المصدر
Bioinorganic Chemistry and Applications
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-04-30
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Five new organotin(IV) complexes of 2-hydroxyacetophenone-2-methylphenylthiosemicarbazone [H2dampt, (1)] with formula [RSnCln-1(dampt)] (where R=Me, n=2 (2); R=Bu, n=2 (3); R=Ph, n=2 (4); R=Me2, n=1 (5); R=Ph2, n=1 (6)) have been synthesized by direct reaction of H2dampt (1) with organotin(IV) chloride(s) in absolute methanol.
The ligand (1) and its organotin(IV) complexes (2–6) were characterized by CHN analyses, molar conductivity, UV-Vis, FT-IR, 1H, 13C, and 119Sn NMR spectral studies.
H2dampt (1) is newly synthesized and has been structurally characterized by X-ray crystallography.
Spectroscopic data suggested that H2dampt (1) is coordinated to the tin(IV) atom through the thiolate-S, azomethine-N, and phenoxide-O atoms; the coordination number of tin is five.
The in vitro antibacterial activity has been evaluated against Staphylococcus aureus, Enterobacter aerogenes, Escherichia coli, and Salmonella typhi.
The screening results have shown that the organotin(IV) complexes (2–6) have better antibacterial activities and have potential as drugs.
Furthermore, it has been shown that diphenyltin(IV) derivative (6) exhibits significantly better activity than the other organotin(IV) derivatives (2–5).
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Salam, M. A.& Affan, M. A.& Saha, Ramkrishna& Ahmad, Fasihuddin Badruddin& Sam, Norrihan. 2012. Synthesis, Characterization and In Vitro Antibacterial Studies of Organotin(IV) Complexes with 2-Hydroxyacetophenone-2-methylphenylthiosemicarbazone (H2dampt). Bioinorganic Chemistry and Applications،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-491542
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Salam, M. A.…[et al.]. Synthesis, Characterization and In Vitro Antibacterial Studies of Organotin(IV) Complexes with 2-Hydroxyacetophenone-2-methylphenylthiosemicarbazone (H2dampt). Bioinorganic Chemistry and Applications No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-491542
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Salam, M. A.& Affan, M. A.& Saha, Ramkrishna& Ahmad, Fasihuddin Badruddin& Sam, Norrihan. Synthesis, Characterization and In Vitro Antibacterial Studies of Organotin(IV) Complexes with 2-Hydroxyacetophenone-2-methylphenylthiosemicarbazone (H2dampt). Bioinorganic Chemistry and Applications. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-491542
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-491542
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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