Characterization of Genes for Beef Marbling Based on Applying Gene Coexpression Network

المؤلفون المشاركون

Park, Hye-Sun
Cho, Yong-Min
Lim, Dajeong
Kim, Nam-Kuk
Chai, Han-Ha
Lee, Seung-Hwan
Kim, Heebal

المصدر

International Journal of Genomics

العدد

المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-10، 10ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2014-01-30

دولة النشر

مصر

عدد الصفحات

10

التخصصات الرئيسية

العلوم الطبيعية والحياتية (متداخلة التخصصات)
الأحياء

الملخص EN

Marbling is an important trait in characterization beef quality and a major factor for determining the price of beef in the Korean beef market.

In particular, marbling is a complex trait and needs a system-level approach for identifying candidate genes related to the trait.

To find the candidate gene associated with marbling, we used a weighted gene coexpression network analysis from the expression value of bovine genes.

Hub genes were identified; they were topologically centered with large degree and BC values in the global network.

We performed gene expression analysis to detect candidate genes in M.

longissimus with divergent marbling phenotype (marbling scores 2 to 7) using qRT-PCR.

The results demonstrate that transmembrane protein 60 (TMEM60) and dihydropyrimidine dehydrogenase (DPYD) are associated with increasing marbling fat.

We suggest that the network-based approach in livestock may be an important method for analyzing the complex effects of candidate genes associated with complex traits like marbling or tenderness.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Lim, Dajeong& Kim, Nam-Kuk& Lee, Seung-Hwan& Park, Hye-Sun& Cho, Yong-Min& Chai, Han-Ha…[et al.]. 2014. Characterization of Genes for Beef Marbling Based on Applying Gene Coexpression Network. International Journal of Genomics،Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-492273

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Lim, Dajeong…[et al.]. Characterization of Genes for Beef Marbling Based on Applying Gene Coexpression Network. International Journal of Genomics No. 2014 (2014), pp.1-10.
https://search.emarefa.net/detail/BIM-492273

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Lim, Dajeong& Kim, Nam-Kuk& Lee, Seung-Hwan& Park, Hye-Sun& Cho, Yong-Min& Chai, Han-Ha…[et al.]. Characterization of Genes for Beef Marbling Based on Applying Gene Coexpression Network. International Journal of Genomics. 2014. Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-492273

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-492273