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Characterization of Genes for Beef Marbling Based on Applying Gene Coexpression Network
Joint Authors
Park, Hye-Sun
Cho, Yong-Min
Lim, Dajeong
Kim, Nam-Kuk
Chai, Han-Ha
Lee, Seung-Hwan
Kim, Heebal
Source
International Journal of Genomics
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-01-30
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Biology
Abstract EN
Marbling is an important trait in characterization beef quality and a major factor for determining the price of beef in the Korean beef market.
In particular, marbling is a complex trait and needs a system-level approach for identifying candidate genes related to the trait.
To find the candidate gene associated with marbling, we used a weighted gene coexpression network analysis from the expression value of bovine genes.
Hub genes were identified; they were topologically centered with large degree and BC values in the global network.
We performed gene expression analysis to detect candidate genes in M.
longissimus with divergent marbling phenotype (marbling scores 2 to 7) using qRT-PCR.
The results demonstrate that transmembrane protein 60 (TMEM60) and dihydropyrimidine dehydrogenase (DPYD) are associated with increasing marbling fat.
We suggest that the network-based approach in livestock may be an important method for analyzing the complex effects of candidate genes associated with complex traits like marbling or tenderness.
American Psychological Association (APA)
Lim, Dajeong& Kim, Nam-Kuk& Lee, Seung-Hwan& Park, Hye-Sun& Cho, Yong-Min& Chai, Han-Ha…[et al.]. 2014. Characterization of Genes for Beef Marbling Based on Applying Gene Coexpression Network. International Journal of Genomics،Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-492273
Modern Language Association (MLA)
Lim, Dajeong…[et al.]. Characterization of Genes for Beef Marbling Based on Applying Gene Coexpression Network. International Journal of Genomics No. 2014 (2014), pp.1-10.
https://search.emarefa.net/detail/BIM-492273
American Medical Association (AMA)
Lim, Dajeong& Kim, Nam-Kuk& Lee, Seung-Hwan& Park, Hye-Sun& Cho, Yong-Min& Chai, Han-Ha…[et al.]. Characterization of Genes for Beef Marbling Based on Applying Gene Coexpression Network. International Journal of Genomics. 2014. Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-492273
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-492273