Uptake and Tolerance of Chemotherapy in Elderly Patients with Small Cell Lung Cancer and Impact on Survival
المؤلفون المشاركون
Winget, Marcy
al-Fayea, Turki M.
Butts, Charles
Fisher, Stacey
Gao, He
المصدر
Journal of Cancer Epidemiology
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-11-29
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
The treatment of elderly cancer patients is complicated by many factors.
We sought to assess the uptake and tolerance of chemotherapy among patients 75 years and older diagnosed with small cell lung cancer (SCLC) in years 2004–2008 in Alberta, Canada, and assess their survival.
All patients who met the above criteria and had an oncologist-consult were included.
Data were obtained from the Alberta Cancer Registry and chart review.
A total of 171 patients were included in the study, 117 (68%) of whom began chemotherapy.
Of those, 52% completed all cycles, 66% did not have any dose reductions, and 31% completed all cycles at the recommended dose.
The risk of death for patients who did not complete all cycles of chemotherapy was 2.72 (95% CI: 1.52–4.87) and for those who completed all cycles but with a reduced dose was 1.02 (95% CI: 0.57–1.82) relative to those who completed chemotherapy at full dose after adjusting for several demographic/clinical factors.
Our results suggest that a significant proportion of elderly patients are able to tolerate chemotherapy and receive a survival benefit from it while those who experience toxicity may receive a survival benefit from a reduction in chemotherapy dose as opposed to stopping treatment.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Fisher, Stacey& al-Fayea, Turki M.& Winget, Marcy& Gao, He& Butts, Charles. 2012. Uptake and Tolerance of Chemotherapy in Elderly Patients with Small Cell Lung Cancer and Impact on Survival. Journal of Cancer Epidemiology،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-492300
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Fisher, Stacey…[et al.]. Uptake and Tolerance of Chemotherapy in Elderly Patients with Small Cell Lung Cancer and Impact on Survival. Journal of Cancer Epidemiology No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-492300
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Fisher, Stacey& al-Fayea, Turki M.& Winget, Marcy& Gao, He& Butts, Charles. Uptake and Tolerance of Chemotherapy in Elderly Patients with Small Cell Lung Cancer and Impact on Survival. Journal of Cancer Epidemiology. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-492300
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-492300
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر