Transformation of Physical DVHs to Radiobiologically Equivalent Ones in Hypofractionated Radiotherapy Analyzing Dosimetric and Clinical Parameters : A Practical Approach for Routine Clinical Practice in Radiation Oncology
المؤلفون المشاركون
Kelekis, Nikolaos
Patatoukas, George
Chaldeopoulos, Demetrios
Thrapsanioti, Zoi
Kouloulias, Vassilis
Efstathopoulos, Efstathios P.
Matsopoulos, George
Platoni, Kalliopi
Karanasiou, Irene
Dilvoi, Maria
المصدر
Computational and Mathematical Methods in Medicine
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-11-19
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Purpose.
The purpose of this study was to transform DVHs from physical to radiobiological ones as well as to evaluate their reliability by correlations of dosimetric and clinical parameters for 50 patients with prostate cancer and 50 patients with breast cancer, who were submitted to Hypofractionated Radiotherapy.
Methods and Materials.
To achieve this transformation, we used both the linear-quadratic model (LQ model) and the Niemierko model.
The outcome of radiobiological DVHs was correlated with acute toxicity score according to EORTC/RTOG criteria.
Results.
Concerning the prostate radiotherapy, there was a significant correlation between RTOG acute rectal toxicity and D50 (P<0.001) and V60 (P=0.001) dosimetric parameters, calculated for α/β=10 Gy.
Moreover, concerning the breast radiotherapy there was a significant correlation between RTOG skin toxicity and V≥60 dosimetric parameter, calculated for both α/β=2.3 Gy (P<0.001) and α/β=10 Gy (P<0.001).
The new tool seems reliable and user-friendly.
Conclusions.
Our proposed model seems user-friendly.
Its reliability in terms of agreement with the presented acute radiation induced toxicity was satisfactory.
However, more patients are needed to extract safe conclusions.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Thrapsanioti, Zoi& Karanasiou, Irene& Platoni, Kalliopi& Efstathopoulos, Efstathios P.& Matsopoulos, George& Dilvoi, Maria…[et al.]. 2013. Transformation of Physical DVHs to Radiobiologically Equivalent Ones in Hypofractionated Radiotherapy Analyzing Dosimetric and Clinical Parameters : A Practical Approach for Routine Clinical Practice in Radiation Oncology. Computational and Mathematical Methods in Medicine،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-492619
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Thrapsanioti, Zoi…[et al.]. Transformation of Physical DVHs to Radiobiologically Equivalent Ones in Hypofractionated Radiotherapy Analyzing Dosimetric and Clinical Parameters : A Practical Approach for Routine Clinical Practice in Radiation Oncology. Computational and Mathematical Methods in Medicine No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-492619
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Thrapsanioti, Zoi& Karanasiou, Irene& Platoni, Kalliopi& Efstathopoulos, Efstathios P.& Matsopoulos, George& Dilvoi, Maria…[et al.]. Transformation of Physical DVHs to Radiobiologically Equivalent Ones in Hypofractionated Radiotherapy Analyzing Dosimetric and Clinical Parameters : A Practical Approach for Routine Clinical Practice in Radiation Oncology. Computational and Mathematical Methods in Medicine. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-492619
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-492619
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر