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Antidiabetic and Antioxidant Properties of Triticum aestivum in Streptozotocin-Induced Diabetic Rats
المؤلفون المشاركون
Mohan, Yogesha
Jesuthankaraj, Grace Nirmala
Ramasamy Thangavelu, Narendhirakannan
المصدر
Advances in Pharmacological Sciences
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-12-14
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
The antidiabetic and antioxidant potential of Triticum aestivum were evaluated by using in vivo methods in normal and streptozotocin-induced diabetic rats.
Diabetes was induced in the Wistar strain albino rats by injecting streptozotocin at a dose of 55 mg/kg body weight.
Ethanolic extracts of Triticum aestivum at doses of 100 mg/kg body weight were administered orally for 30 days.
Various parameters were studied and the treatment group with the extract showed a significant increase in the liver glycogen and a significant decrease in fasting blood glucose, glycosylated hemoglobin levels, and serum marker enzyme levels.
The total cholesterol and serum triglycerides levels, low density lipoprotein, and very low density lipoprotein were also significantly reduced and the high density lipoprotein level was significantly increased upon treatment with the Triticum aestivum ethanol extract.
A significant decrease in the levels of lipid peroxides, superoxide dismutase, and glutathione peroxidise and increase in the levels of vitamin E, catalase, and reduced glutathione were observed in Triticum aestivum treated diabetic rats.
Thus, from this study we conclude that ethanolic extract of Triticum aestivum exhibited significant antihyperglycemic, hypolipidemic, and antioxidant activities in streptozotocin-induced diabetic rats.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Mohan, Yogesha& Jesuthankaraj, Grace Nirmala& Ramasamy Thangavelu, Narendhirakannan. 2013. Antidiabetic and Antioxidant Properties of Triticum aestivum in Streptozotocin-Induced Diabetic Rats. Advances in Pharmacological Sciences،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-492871
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Mohan, Yogesha…[et al.]. Antidiabetic and Antioxidant Properties of Triticum aestivum in Streptozotocin-Induced Diabetic Rats. Advances in Pharmacological Sciences No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-492871
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Mohan, Yogesha& Jesuthankaraj, Grace Nirmala& Ramasamy Thangavelu, Narendhirakannan. Antidiabetic and Antioxidant Properties of Triticum aestivum in Streptozotocin-Induced Diabetic Rats. Advances in Pharmacological Sciences. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-492871
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-492871
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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