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The Link between Hypersensitivity Syndrome Reaction Development and Human Herpes Virus-6 Reactivation
المؤلفون المشاركون
Neuman, Manuela G.
Nanau, Radu M.
Pritchett, Joshua C.
المصدر
International Journal of Hepatology
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-19، 19ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-05-16
دولة النشر
مصر
عدد الصفحات
19
التخصصات الرئيسية
الملخص EN
Background.
There are challenges in the clinical diagnosis of drug-induced injury and in obtaining information on the reactivation of human herpes viruses (HHV) during idiosyncratic adverse drug reactions.
Objectives.
(i) To develop a unified list of drugs incriminated in drug-induced hepatotoxicity and severe cutaneous reactions, in which drug hypersensitivity leads to HHV-6 reactivation and further complication of therapy and recovery and (ii) to supplement the already available data on reporting frequencies of liver- or skin-induced cases with knowledge of individual case reports, including HHV-6 reactivation and briefly introducing chromosomally integrated HHV-6.
Data Sources and Extraction.
Drugs identified as causes of (i) idiosyncratic reactions, (ii) drug-induced hypersensitivity, drug-induced hepatotoxicity, acute liver failure, and Stevens-Johnson syndrome, and (iii) human herpes virus reactivation in PubMed since 1997 have been collected and discussed.
Results.
Data presented in this paper show that HHV-6 reactivation is associated with more severe organ involvement and a prolonged course of disease.
Conclusion.
This analysis of HHV-6 reactivation associated with drug-induced severe cutaneous reactions and hepatotoxicity will aid in causality assessment and clinical diagnosis of possible life-threatening events and will provide a basis for further patient characterization and therapy.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Pritchett, Joshua C.& Nanau, Radu M.& Neuman, Manuela G.. 2012. The Link between Hypersensitivity Syndrome Reaction Development and Human Herpes Virus-6 Reactivation. International Journal of Hepatology،Vol. 2012, no. 2012, pp.1-19.
https://search.emarefa.net/detail/BIM-493404
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Pritchett, Joshua C.…[et al.]. The Link between Hypersensitivity Syndrome Reaction Development and Human Herpes Virus-6 Reactivation. International Journal of Hepatology No. 2012 (2012), pp.1-19.
https://search.emarefa.net/detail/BIM-493404
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Pritchett, Joshua C.& Nanau, Radu M.& Neuman, Manuela G.. The Link between Hypersensitivity Syndrome Reaction Development and Human Herpes Virus-6 Reactivation. International Journal of Hepatology. 2012. Vol. 2012, no. 2012, pp.1-19.
https://search.emarefa.net/detail/BIM-493404
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-493404
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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