Aggressive Treatment of Patients with Metastatic Colorectal Cancer Increases Survival : A Scandinavian Single-Center Experience
المؤلفون المشاركون
Taskén, Kjetil
Brudvik, Kristoffer Watten
Seeberg, Lars Thomas
Labori, Knut Jørgen
Bjørnbeth, Bjørn Atle
Waage, Anne
Bains, Simer Jit
Aandahl, Einar Martin
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-06-06
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Background.
We examined overall and disease-free survivals in a cohort of patients subjected to resection of liver metastasis from colorectal cancer (CRLM) in a 10-year period when new treatment strategies were implemented.
Methods.
Data from 239 consecutive patients selected for liver resection of CRLM during the period from 2002 to 2011 at a single center were used to estimate overall and disease-free survival.
The results were assessed against new treatment strategies and established risk factors.
Results.
The 5-year cumulative overall and disease-free survivals were 46 and 24%.
The overall survival was the same after reresection, independently of the number of prior resections and irrespectively of the location of the recurrent disease.
The time intervals between each recurrence were similar (11 ± 1 months).
Patients with high tumor load given neoadjuvant chemotherapy had comparable survival to those with less extensive disease without neoadjuvant chemotherapy.
Positive resection margin or resectable extrahepatic disease did not affect overall survival.
Conclusion.
Our data support that one still, and perhaps to an even greater extent, should seek an aggressive therapeutic strategy to achieve resectable status for recurrent hepatic and extrahepatic metastases.
The data should be viewed in the context of recent advances in the understanding of cancer biology and the metastatic process.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Brudvik, Kristoffer Watten& Bains, Simer Jit& Seeberg, Lars Thomas& Labori, Knut Jørgen& Waage, Anne& Taskén, Kjetil…[et al.]. 2013. Aggressive Treatment of Patients with Metastatic Colorectal Cancer Increases Survival : A Scandinavian Single-Center Experience. HPB Surgery،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-493814
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Brudvik, Kristoffer Watten…[et al.]. Aggressive Treatment of Patients with Metastatic Colorectal Cancer Increases Survival : A Scandinavian Single-Center Experience. HPB Surgery No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-493814
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Brudvik, Kristoffer Watten& Bains, Simer Jit& Seeberg, Lars Thomas& Labori, Knut Jørgen& Waage, Anne& Taskén, Kjetil…[et al.]. Aggressive Treatment of Patients with Metastatic Colorectal Cancer Increases Survival : A Scandinavian Single-Center Experience. HPB Surgery. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-493814
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-493814
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر