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A Large Cohort Study of Hypothyroidism and Hyperthyroidism in Relation to Gynecologic Cancers
المؤلفون المشاركون
Tworoger, Shelley S.
Rosner, Bernard
Alexander, Erik
Kang, Jae H.
De Vivo, Immaculata
Curhan, Gary
Kueck, Angela S.
Stevens, Richard
المصدر
Obstetrics and Gynecology International
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-07-15
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Background.
Thyroid status may influence tumorigenesis of gynecologic cancers, yet epidemiologic studies of this relationship are limited and inconsistent.
Methods.
We evaluated the association of self-reported history of physician-diagnosed hypothyroidism and hyperthyroidism with medical-record confirmed endometrial (EC; all invasive adenocarcinomas) and ovarian cancer (OC; epithelial ovarian or peritoneal cancers) in Nurses' Health Study (NHS) from 1976 to 2010 and NHSII from 1989 to 2011.
Cox proportional hazard models were used to estimate multivariable rate ratios (RRs) and 95% confidence intervals based on pooled cohort data.
Results.
We confirmed 1314 incident cases of EC and 1150 cases of OC.
Neither a history of hypothyroidism nor hyperthyroidism was significantly associated with risk of EC or OC.
However, having a history of hypothyroidism for 8+ years (median) was nonsignificantly inversely associated with EC (RR = 0.81; 95% CI = 0.63–1.04; P-trend with history duration = 0.11) and OC (RR = 0.87, 95% CI = 0.66–1.15; P-trend = 0.13).
Having a history of hyperthyroidism for 6+ years (median) was non-significantly positively associated with EC (RR = 1.69; 95% CI = 0.86–3.30; P-trend = 0.12) but not OC (RR = 1.12; 95% CI = 0.46–2.72; P-trend = 0.95).
Conclusions.
A history of hypothyroidism or hyperthyroidism was not significantly associated with risk of EC or OC.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kang, Jae H.& Kueck, Angela S.& Stevens, Richard& Curhan, Gary& De Vivo, Immaculata& Rosner, Bernard…[et al.]. 2013. A Large Cohort Study of Hypothyroidism and Hyperthyroidism in Relation to Gynecologic Cancers. Obstetrics and Gynecology International،Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-495246
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kang, Jae H.…[et al.]. A Large Cohort Study of Hypothyroidism and Hyperthyroidism in Relation to Gynecologic Cancers. Obstetrics and Gynecology International No. 2013 (2013), pp.1-10.
https://search.emarefa.net/detail/BIM-495246
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kang, Jae H.& Kueck, Angela S.& Stevens, Richard& Curhan, Gary& De Vivo, Immaculata& Rosner, Bernard…[et al.]. A Large Cohort Study of Hypothyroidism and Hyperthyroidism in Relation to Gynecologic Cancers. Obstetrics and Gynecology International. 2013. Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-495246
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-495246
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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