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Renal Transplantation in Systemic Lupus Erythematosus : Outcome and Prognostic Factors in 50 Cases from a Single Centre
المؤلفون المشاركون
Glucksmann, Constanza
Cervera, Ricard
Ercilla, Guadalupe
Oppenheimer, Federico
Sanchez-Marcos, Carolina
Cairoli, Ernesto
Espinosa, Gerard
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-06-11
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
End-stage renal disease (ESRD) is an important cause of morbidity and mortality in patients with systemic lupus erythematosus (SLE).
Objectives.
To analyze the outcome and prognostic factors of renal transplantation in patients with ESRD due to SLE from January 1986 to December 2013 in a single center.
Results.
Fifty renal transplantations were performed in 40 SLE patients (32 female (80%), mean age at transplantation 36 ± 10.4 years).
The most frequent lupus nephropathy was type IV (72.2%).
Graft failure occurred in a total of 15 (30%) transplantations and the causes of graft failure were chronic allograft nephropathy (n=12), acute rejection (n=2), and chronic humoral rejection (1).
The death-censored graft survival rates were 93.9% at 1 year, 81.5% at 5 years, and 67.6% at the end of study.
The presence of deceased donor allograft (P=0.007) and positive anti-HCV antibodies (P=0.001) negatively influence the survival of the renal transplant.
The patient survival rate was 91.4% at the end of the study.
Recurrence of lupus nephritis in renal allograft was observed in one patient.
Conclusion.
Renal transplantation is a good alternative for renal replacement therapy in patients with SLE.
In our cohort, the presence of anti-HCV antibodies and the type of donor source were related to the development of graft failure.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Cairoli, Ernesto& Sanchez-Marcos, Carolina& Espinosa, Gerard& Glucksmann, Constanza& Ercilla, Guadalupe& Oppenheimer, Federico…[et al.]. 2014. Renal Transplantation in Systemic Lupus Erythematosus : Outcome and Prognostic Factors in 50 Cases from a Single Centre. BioMed Research International،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-495386
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Cairoli, Ernesto…[et al.]. Renal Transplantation in Systemic Lupus Erythematosus : Outcome and Prognostic Factors in 50 Cases from a Single Centre. BioMed Research International No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-495386
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Cairoli, Ernesto& Sanchez-Marcos, Carolina& Espinosa, Gerard& Glucksmann, Constanza& Ercilla, Guadalupe& Oppenheimer, Federico…[et al.]. Renal Transplantation in Systemic Lupus Erythematosus : Outcome and Prognostic Factors in 50 Cases from a Single Centre. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-495386
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-495386
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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