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Postangioplasty Restenosis Followed with Magnetic Resonance Imaging in an Atherosclerotic Rabbit Model
المؤلفون المشاركون
Hänni, Mari
Smedby, Örjan
Leppänen, Olli
المصدر
International Journal of Biomedical Imaging
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-12-19
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Rationale and Objectives.
Testing a quantitative, noninvasive method to assess postangioplasty vessel wall changes in an animal model.
Material and Methods.
Six New Zealand white rabbits were subjected to atherosclerotic injury, including cholesterol-enriched diet, deendothelialization, and percutaneous transluminal angioplasty (PTA) in the distal part of abdominal aorta (four weeks after deendothelialization).
The animals were examined with a 1.5T MRI scanner at three times as follows: baseline (six weeks after diet start and two days after PTA) and four weeks and 10 weeks after-PTA.
Inflow angiosequence (M2DI) and proton-density-weighted sequence (PDW) were performed to examine the aorta with axial slices.
To identify the inner and outer vessel wall boundaries, a dynamic contour algorithm (Gradient Vector Flow Snakes) was applied to the images, followed by calculation of the vessel wall dimensions.
The results were compared with histopathological analysis.
Results.
The wall thickness in the lesion was significantly higher than in the control region at 4 and 10 weeks, reflecting induction of experimentally created after-angioplasty lesion.
At baseline, no significant difference between the two regions was present.
Conclusions.
It is possible to follow the development of vessel wall changes after-PTA with MRI in this rabbit model.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hänni, Mari& Leppänen, Olli& Smedby, Örjan. 2012. Postangioplasty Restenosis Followed with Magnetic Resonance Imaging in an Atherosclerotic Rabbit Model. International Journal of Biomedical Imaging،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-495485
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hänni, Mari…[et al.]. Postangioplasty Restenosis Followed with Magnetic Resonance Imaging in an Atherosclerotic Rabbit Model. International Journal of Biomedical Imaging No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-495485
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hänni, Mari& Leppänen, Olli& Smedby, Örjan. Postangioplasty Restenosis Followed with Magnetic Resonance Imaging in an Atherosclerotic Rabbit Model. International Journal of Biomedical Imaging. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-495485
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-495485
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
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