Further Increase in the Expression of Activation Markers on Monocyte-Derived Dendritic Cells in Coronary Artery Disease Patients with Ectasia Compared to Patients with Coronary Artery Disease Alone
المؤلفون المشاركون
Aydin, Mustafa
Yildirim, Nesligul
Arasli, Muhammad
Tekin, Ishak Ozel
المصدر
العدد
المجلد 2010، العدد 2010 (31 ديسمبر/كانون الأول 2010)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2010-06-14
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
Coronary artery ectasia (CAE) is defined as localized or diffuse dilation of the coronary arteries.
There are scarce data about the role of dendritic cells in CAE development.
In this study we investigated the activation markers on the surface of monocyte-derived dendritic cells (mDCs) in coronary artery disease (CAD) patients with or without CAE.
Method.
The study consisted of 6 patients who had obstructive CAD with CAE, 6 CAD patients without CAE and 6 subjects with angiographically normal coronary arteries.
mDCs were cultivated from peripheral blood monocytes.
Surface activation markers were detected by flow cytometry.
Results.
CAD patients with CAE were detected to have significantly higher mean fluorescence intensities of CD11b, CD11c, CD54 , CD83, CD86 and MHC Class II molecules on mDCs in comparison to CAD patients without CAE and normal controls (P<.001 for all).
A significant positive correlation was found between the number of vessels with CAE and the levels of CD11c, CD86, and MHC Class II molecules.
Conclusion.
mDCs display an increased cell surface concentration of activation molecules in CAD patients with CAE compared to patients with CAD alone.
DC activation may play an important role for CAE development in patients with CAD.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yildirim, Nesligul& Tekin, Ishak Ozel& Arasli, Muhammad& Aydin, Mustafa. 2010. Further Increase in the Expression of Activation Markers on Monocyte-Derived Dendritic Cells in Coronary Artery Disease Patients with Ectasia Compared to Patients with Coronary Artery Disease Alone. Mediators of Inflammation،Vol. 2010, no. 2010, pp.1-6.
https://search.emarefa.net/detail/BIM-495620
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yildirim, Nesligul…[et al.]. Further Increase in the Expression of Activation Markers on Monocyte-Derived Dendritic Cells in Coronary Artery Disease Patients with Ectasia Compared to Patients with Coronary Artery Disease Alone. Mediators of Inflammation No. 2010 (2010), pp.1-6.
https://search.emarefa.net/detail/BIM-495620
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yildirim, Nesligul& Tekin, Ishak Ozel& Arasli, Muhammad& Aydin, Mustafa. Further Increase in the Expression of Activation Markers on Monocyte-Derived Dendritic Cells in Coronary Artery Disease Patients with Ectasia Compared to Patients with Coronary Artery Disease Alone. Mediators of Inflammation. 2010. Vol. 2010, no. 2010, pp.1-6.
https://search.emarefa.net/detail/BIM-495620
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-495620
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر