Extracellular Matrix Modulates Angiogenesis in Physiological and Pathological Conditions

المؤلفون المشاركون

Maruotti, Nicola
Neve, Anna
Cantatore, Francesco Paolo
Ribatti, Domenico
Corrado, Addolorata

المصدر

BioMed Research International

العدد

المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-10، 10ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2014-05-18

دولة النشر

مصر

عدد الصفحات

10

التخصصات الرئيسية

الطب البشري

الملخص EN

Angiogenesis is a multistep process driven by a wide range of positive and negative regulatory factors.

Extracellular matrix (ECM) plays a crucial role in the regulation of this process.

The degradation of ECM, occurring in response to an angiogenic stimulus, leads to degradation or partial modification of matrix molecules, release of soluble factors, and exposure of cryptic sites with pro- and/or antiangiogenic activity.

ECM molecules and fragments, resulting from proteolysis, can also act directly as inflammatory stimuli, and this can explain the exacerbated angiogenesis that drives and maintains several inflammatory diseases.

In this review we have summarized some of the more recent literature data concerning the molecular control of ECM in angiogenesis in both physiological and pathological conditions.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Neve, Anna& Cantatore, Francesco Paolo& Maruotti, Nicola& Corrado, Addolorata& Ribatti, Domenico. 2014. Extracellular Matrix Modulates Angiogenesis in Physiological and Pathological Conditions. BioMed Research International،Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-496214

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Neve, Anna…[et al.]. Extracellular Matrix Modulates Angiogenesis in Physiological and Pathological Conditions. BioMed Research International No. 2014 (2014), pp.1-10.
https://search.emarefa.net/detail/BIM-496214

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Neve, Anna& Cantatore, Francesco Paolo& Maruotti, Nicola& Corrado, Addolorata& Ribatti, Domenico. Extracellular Matrix Modulates Angiogenesis in Physiological and Pathological Conditions. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-496214

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-496214