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The Correlation between Microsatellite Instability and the Features of Sporadic Colorectal Cancer in the North Part of Iran
المؤلفون المشاركون
Aminian, Keyvan
Seighalani, Ramin
Tarang, Alireza
Faghani, Masoumeh
Mansour-Ghanaei, Fariborz
Javadi, Azadeh
Fakhrieh Asl, Saba
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-11-19
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
The aim of this study was to determine the correlation between MSI and sporadic colorectal cancer in Guilan province, North part of Iran.
Materials and Methods.
A total of 96 patients who underwent resection for sporadic colorectal cancer in Guilan province were studied.
No patients had positive family history of cancers.
The frequencies of MSI were analyzed by testing the BAT-26 and BAT-25 markers.
Results.
MSI analysis revealed that 22.9% of the tumors (22 patients) were microsatellite instability positive and 77.1% (74 patients) were microsatellite instability negative.
The highest rate of MSI (40.9%) was found in the rectal region.
MSI-H status was seen more frequently in distal tumors (P=0.04, odds ratio = 3.13, 0.96–10.14).
Conclusions.
Distal tumor location and MSI may associate with special clinicopathological features.
It seems that there may be correlation with underlying genetic and immunologic mechanisms.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Faghani, Masoumeh& Fakhrieh Asl, Saba& Mansour-Ghanaei, Fariborz& Aminian, Keyvan& Tarang, Alireza& Seighalani, Ramin…[et al.]. 2012. The Correlation between Microsatellite Instability and the Features of Sporadic Colorectal Cancer in the North Part of Iran. Gastroenterology Research and Practice،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-496236
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Faghani, Masoumeh…[et al.]. The Correlation between Microsatellite Instability and the Features of Sporadic Colorectal Cancer in the North Part of Iran. Gastroenterology Research and Practice No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-496236
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Faghani, Masoumeh& Fakhrieh Asl, Saba& Mansour-Ghanaei, Fariborz& Aminian, Keyvan& Tarang, Alireza& Seighalani, Ramin…[et al.]. The Correlation between Microsatellite Instability and the Features of Sporadic Colorectal Cancer in the North Part of Iran. Gastroenterology Research and Practice. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-496236
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-496236
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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