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Traffic Control of Bacteria-Derived Molecules : A New System of Host-Bacterial Crosstalk
المؤلفون المشاركون
Kohgo, Yutaka
Fujiya, Mikihiro
Konishi, Hiroaki
المصدر
International Journal of Cell Biology
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-03-31
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Virulent microorganisms, such as pathogenic bacteria and viruses, are recognized by pattern recognition receptors (PRRs), including toll-like receptors (TLRs) and nucleotide-binding oligomerization-domain proteins (NODs), and induce inflammatory responses in mammalian hosts.
Conversely, commensal bacteria and probiotics, which symbiotically confer health benefits on the host organisms, can lodge in the host intestinal tract without inducing intestinal inflammation.
Recent advances in investigations concerning host-microbial interactions have shown that some effector molecules secreted from beneficial bacteria activate cell survival pathways, such as those mediated by p38 MAPK and Akt, and bring health benefits to mammalian hosts.
It is noteworthy that such bacteria-derived molecules are taken into the intestinal epithelia through a transport or endocytosis system, thereafter exhibiting their beneficial effects.
Understanding this traffic control process can aid in the comprehension of host and microbe interactions and may provide new insight to clarify the pathogenesis of intestinal disorders.
This paper highlights the intestinal trafficking systems of bacteria-derived molecules that affect the bacterial functions and modulate epithelial signaling cascades.
The latter mechanism may contribute to the maintenance of intestinal homeostasis by improving the host damage induced by virulence factors and various disease states.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Konishi, Hiroaki& Fujiya, Mikihiro& Kohgo, Yutaka. 2013. Traffic Control of Bacteria-Derived Molecules : A New System of Host-Bacterial Crosstalk. International Journal of Cell Biology،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-496316
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Konishi, Hiroaki…[et al.]. Traffic Control of Bacteria-Derived Molecules : A New System of Host-Bacterial Crosstalk. International Journal of Cell Biology No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-496316
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Konishi, Hiroaki& Fujiya, Mikihiro& Kohgo, Yutaka. Traffic Control of Bacteria-Derived Molecules : A New System of Host-Bacterial Crosstalk. International Journal of Cell Biology. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-496316
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-496316
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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