Ductal Carcinoma In Situ of the Breast : A Surgical Perspective
المؤلف
المصدر
International Journal of Surgical Oncology
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-09-04
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
Ductal carcinoma in situ (DCIS) of the breast is a heterogeneous neoplasm with invasive potential.
Risk factors include age, family history, hormone replacement therapy, genetic mutation, and patient lifestyle.
The incidence of DCIS has increased due to more widespread use of screening and diagnostic mammography; almost 80% of cases are diagnosed with imaging with final diagnosis established by biopsy and histological examination.
There are various classification systems used for DCIS, the most recent of which is based on the presence of intraepithelial neoplasia of the ductal epithelium (DIN).
A number of molecular assays are now available that can identify high-risk patients as well as help establish the prognosis of patients with diagnosed DCIS.
Current surgical treatment options include total mastectomy, simple lumpectomy in very low-risk patients, and lumpectomy with radiation.
Adjuvant therapy is tailored based on the molecular profile of the neoplasm and can include aromatase inhibitors, anti-estrogen, anti-progesterone (or a combination of antiestrogen and antiprogesterone), and HER2 neu suppression therapy.
Chemopreventive therapies are under investigation for DCIS, as are various molecular-targeted drugs.
It is anticipated that new biologic agents, when combined with hormonal agents such as SERMs and aromatase inhibitors, may one day prevent all forms of breast cancer.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Badruddoja, Mohammed. 2012. Ductal Carcinoma In Situ of the Breast : A Surgical Perspective. International Journal of Surgical Oncology،Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-496689
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Badruddoja, Mohammed. Ductal Carcinoma In Situ of the Breast : A Surgical Perspective. International Journal of Surgical Oncology No. 2012 (2012), pp.1-12.
https://search.emarefa.net/detail/BIM-496689
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Badruddoja, Mohammed. Ductal Carcinoma In Situ of the Breast : A Surgical Perspective. International Journal of Surgical Oncology. 2012. Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-496689
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-496689
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر