![](/images/graphics-bg.png)
Effects of Spirulina on Cyclophosphamide-Induced Ovarian Toxicity in Rats : Biochemical and Histomorphometric Evaluation of the Ovary
المؤلفون المشاركون
Aksungar, Fehime
Celik, Aygen
Ilter, Erdin
Midi, Ahmet
Sezgin, Gulbuz
Deveci, Ugur
Yener, Nese Arzu
Sinanoglu, Orhun
المصدر
Biochemistry Research International
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-05-09
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Cyclophosphamide (Cyc) is known to cause ovotoxicity and infertility in women.
Our aim is to investigate the possible ovotoxic effects of Cyc and possible antioxidant and protective effects of blue-green algae, Spirulina (Sp), in rat ovaries.
Eighteen rats were given: group I (n=6, control); group II (n=6, CP), a single dose Cyc; group III (n=6, Sp+Cyc), 7 days Sp+single dose Cyc.
Tissue malondialdehyde (MDA) levels, superoxide dismutase (SOD), and catalase (CAT) activities are assessed biochemically.
Normal and atretic primordial and primary follicle counts for all sections obtained for each ovary are calculated.
Mean number of follicle counts for each group are compared.
In Sp+Cyc group, tissue MDA levels were significantly lower than those in the CP and higher than those in the C group (CP>Sp+Cyc>C).
Tissue SOD activity was significantly higher in Sp+Cyc group than that in the CP group and lower than that in the C group (C>Sp+Cyc>C).
No statistically significant difference was found between the ovarian CAT activities in any group.
Histomorphometrically, there was also no significant difference between the mean numbers of normal and atretic small follicle counts.
Our results suggest that single dose Cyc has adverse effects on oxidant status of the ovaries and Sp has protective effects in Cyc-induced ovotoxicity.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yener, Nese Arzu& Sinanoglu, Orhun& Ilter, Erdin& Celik, Aygen& Sezgin, Gulbuz& Midi, Ahmet…[et al.]. 2013. Effects of Spirulina on Cyclophosphamide-Induced Ovarian Toxicity in Rats : Biochemical and Histomorphometric Evaluation of the Ovary. Biochemistry Research International،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-496964
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yener, Nese Arzu…[et al.]. Effects of Spirulina on Cyclophosphamide-Induced Ovarian Toxicity in Rats : Biochemical and Histomorphometric Evaluation of the Ovary. Biochemistry Research International No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-496964
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yener, Nese Arzu& Sinanoglu, Orhun& Ilter, Erdin& Celik, Aygen& Sezgin, Gulbuz& Midi, Ahmet…[et al.]. Effects of Spirulina on Cyclophosphamide-Induced Ovarian Toxicity in Rats : Biochemical and Histomorphometric Evaluation of the Ovary. Biochemistry Research International. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-496964
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-496964
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)