Efficacy and Safety of Gwakhyangjeonggi-San Retention Enema in Normal Rats and Spontaneously Hypertensive Rats
المؤلفون المشاركون
Song, Eunyoung
Park, Jaewoo
Lee, Euiju
Yoo, Junghee
Shin, Seungwon
Kwon, Jinhyeok
Bu, Yongmin
Lee, Junhee
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-06-17
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
The purpose of this study is to establish a protocol of retention-enema experiments and evaluate the antihypertensive effect and the safety of Gwakhyangjeonggi-san retention enema.
Normal and spontaneously hypertensive rats (SHRs) were divided into treatment and control groups, respectively.
We applied the Gwakhyangjeonggi-san extract by decoction and 0.9% NaCl in each group, estimated the blood pressure and body weight, and performed HPLC analysis.
ALT, AST, BUN, and creatinine were examined.
The systolic blood pressure within each group in normal rats differed significantly in time effect, and so did the diastolic blood pressure in the treatment group of normal rats.
The systolic, diastolic, and mean blood pressure showed significant differences in group effect in the treatment group of the SHRs.
The time effect of the body weight in both groups of normal rats differed significantly, so did group × time and time effects in both groups of SHRs.
AST, ALT, BUN, and creatinine showed no significant difference between groups.
We concluded that the Gwakhyangjeonggi-san retention enema has a hypotensive effect in normal rats within the regular range of blood pressure, but an antihypertensive effect in SHRs.
Also, the intervention is safe and does not affect the liver and kidney functions in normal rats.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Song, Eunyoung& Lee, Euiju& Bu, Yongmin& Lee, Junhee& Shin, Seungwon& Yoo, Junghee…[et al.]. 2013. Efficacy and Safety of Gwakhyangjeonggi-San Retention Enema in Normal Rats and Spontaneously Hypertensive Rats. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-497112
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Song, Eunyoung…[et al.]. Efficacy and Safety of Gwakhyangjeonggi-San Retention Enema in Normal Rats and Spontaneously Hypertensive Rats. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-10.
https://search.emarefa.net/detail/BIM-497112
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Song, Eunyoung& Lee, Euiju& Bu, Yongmin& Lee, Junhee& Shin, Seungwon& Yoo, Junghee…[et al.]. Efficacy and Safety of Gwakhyangjeonggi-San Retention Enema in Normal Rats and Spontaneously Hypertensive Rats. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-497112
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-497112
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر