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Biological Characterization and Pluripotent Identification of Sheep Dermis-Derived Mesenchymal StemProgenitor Cells
المؤلفون المشاركون
Zhang, Ping
Zhang, Wenxiu
Guan, Weijun
He, Xiaohong
Li, Changli
Ma, Yuehui
Li, Xiangchen
Pu, Yabin
Cui, Peng
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-14، 14ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-05-18
دولة النشر
مصر
عدد الصفحات
14
التخصصات الرئيسية
الملخص EN
Dermis-derived mesenchymal stem/progenitor cells (DMS/PCs) were a multipotential stem cell population, which has potential applications in the tissue damage repair and skin transplant.
Although a large number of studies deal with the human DMS/PCs self-renewal and regulation, however, the study of livestock-derived DMS/PCs has rarely been reported.
Here, sheep DMS/PCs were isolated from one-month-old sheep embryos and studied at the cellular and molecular level.
And then the DMS/PCs biological characteristics were analysed by RT-PCR and immunofluorescence.
Experimental results showed that DMS/PCs could be expanded for 48 passages and the cells viability and hereditary character were steady.
In addition, the DMS/PCs maker β-integrin, CD71, CD44, and CD73 were expressed positively through RT-PCR and immunofluorescence.
Passage 3 DMS/PCs were successfully induced to differentiate into adipocytes, osteoblasts, chondrocytes, and neurocytes, respectively.
The above results suggest that DMS/PCs not only have strong self-renewal capacity but also have the potential to differentiate into adipocytes, osteoblasts, chondrocytes, and neurocytes.
The study provides theoretical basis and experimental evidence for potential clinical application.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Cui, Peng& He, Xiaohong& Pu, Yabin& Zhang, Wenxiu& Zhang, Ping& Li, Changli…[et al.]. 2014. Biological Characterization and Pluripotent Identification of Sheep Dermis-Derived Mesenchymal StemProgenitor Cells. BioMed Research International،Vol. 2014, no. 2014, pp.1-14.
https://search.emarefa.net/detail/BIM-497985
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Cui, Peng…[et al.]. Biological Characterization and Pluripotent Identification of Sheep Dermis-Derived Mesenchymal StemProgenitor Cells. BioMed Research International No. 2014 (2014), pp.1-14.
https://search.emarefa.net/detail/BIM-497985
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Cui, Peng& He, Xiaohong& Pu, Yabin& Zhang, Wenxiu& Zhang, Ping& Li, Changli…[et al.]. Biological Characterization and Pluripotent Identification of Sheep Dermis-Derived Mesenchymal StemProgenitor Cells. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-14.
https://search.emarefa.net/detail/BIM-497985
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-497985
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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