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Clinical Outcomes after Treatment of Periodontal Intrabony Defects with Nanocrystalline Hydroxyapatite (Ostim) or Enamel Matrix Derivatives (Emdogain) : A Randomized Controlled Clinical Trial
المؤلفون المشاركون
Hoffmann, Thomas
al-Machot, Elyan
Lorenz, Katrin
Noack, Barbara
Khalili, Ihssan
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-02-09
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Introduction.
Periodontitis is an inflammatory process in response to dental biofilm and leads to periodontal tissue destruction.
The aim of this study was the comparison of outcomes using either an enamel matrix derivative (EMD) or a nanocrystalline hydroxyapatite (NHA) in regenerative periodontal therapy after 6 and 12 months.
Methods.
Using a parallel group, prospective randomized study design, we enrolled 19 patients in each group.
The primary outcome was bone fill after 12 months.
Attachment gain, probing pocket depth (PPD) reduction, and recession were secondary variables.
Additionally, early wound healing and adverse events were assessed.
Data analysis included test of noninferiority of NHA group (test) compared to EMD group (reference) in bone fill.
Differences in means of secondary variables were compared by paired t-test, frequency data by exact χ2 test.
Results.
Both groups showed significant bone fill, reduction of PPD, increase in recession, and gain of attachment after 6 and 12 months.
No significant differences between groups were found at any time point.
Adverse events were comparable between both groups with a tendency of more complaints in the NHA group.
Conclusion.
The clinical outcomes were similar in both groups.
EMD could have some advantage compared to NHA regarding patients comfort and adverse events.
The trial is registered with ClinicalTrials.gov NCT00757159.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Machot, Elyan& Hoffmann, Thomas& Lorenz, Katrin& Khalili, Ihssan& Noack, Barbara. 2014. Clinical Outcomes after Treatment of Periodontal Intrabony Defects with Nanocrystalline Hydroxyapatite (Ostim) or Enamel Matrix Derivatives (Emdogain) : A Randomized Controlled Clinical Trial. BioMed Research International،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-497996
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Machot, Elyan…[et al.]. Clinical Outcomes after Treatment of Periodontal Intrabony Defects with Nanocrystalline Hydroxyapatite (Ostim) or Enamel Matrix Derivatives (Emdogain) : A Randomized Controlled Clinical Trial. BioMed Research International No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-497996
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Machot, Elyan& Hoffmann, Thomas& Lorenz, Katrin& Khalili, Ihssan& Noack, Barbara. Clinical Outcomes after Treatment of Periodontal Intrabony Defects with Nanocrystalline Hydroxyapatite (Ostim) or Enamel Matrix Derivatives (Emdogain) : A Randomized Controlled Clinical Trial. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-497996
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-497996
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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