![](/images/graphics-bg.png)
Achyrocline satureioides (Lam.) D.C. Hydroalcoholic Extract Inhibits Neutrophil Functions Related to Innate Host Defense
المؤلفون المشاركون
Cogliati, Bruno
Niero, Rivaldo
Wagner, Theodoro Marcel
Andrade, Sérgio Faloni de
Machado, Isabel Daufenback
Santin, José Roberto
Ferraz-de-Paula, Viviane
Barioni, Eric Diego
Farsky, Sandra Helena Poliselli
Machado, Marina da Silva
Rodrigues, Stephen Fernandes de Paula
Corrêa dos Santos, Matheus
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-02-11
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
Achyrocline satureioides (Lam.) D.C.
is a herb native to South America, and its inflorescences are popularly employed to treat inflammatory diseases.
Here, the effects of the in vivo actions of the hydroalcoholic extract obtained from inflorescences of A.
satureioides on neutrophil trafficking into inflamed tissue were investigated.
Male Wistar rats were orally treated with A.
satureioides extract, and inflammation was induced one hour later by lipopolysaccharide injection into the subcutaneous tissue.
The number of leukocytes and the amount of chemotactic mediators were quantified in the inflammatory exudate, and adhesion molecule and toll-like receptor 4 (TLR-4) expressions and phorbol-myristate-acetate- (PMA-) stimulated oxidative burst were quantified in circulating neutrophils.
Leukocyte-endothelial interactions were quantified in the mesentery tissue.
Enzymes and tissue morphology of the liver and kidney were evaluated.
Treatment with A.
satureioides extract reduced neutrophil influx and secretion of leukotriene B4 and CINC-1 in the exudates, the number of rolling and adhered leukocytes in the mesentery postcapillary venules, neutrophil L-selectin, β2-integrin and TLR-4 expression, and oxidative burst, but did not cause an alteration in the morphology and activities of liver and kidney.
Together, the data show that A.
satureioides extract inhibits neutrophil functions related to the innate response and does not cause systemic toxicity.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Barioni, Eric Diego& Santin, José Roberto& Machado, Isabel Daufenback& Rodrigues, Stephen Fernandes de Paula& Ferraz-de-Paula, Viviane& Wagner, Theodoro Marcel…[et al.]. 2013. Achyrocline satureioides (Lam.) D.C. Hydroalcoholic Extract Inhibits Neutrophil Functions Related to Innate Host Defense. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-498125
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Barioni, Eric Diego…[et al.]. Achyrocline satureioides (Lam.) D.C. Hydroalcoholic Extract Inhibits Neutrophil Functions Related to Innate Host Defense. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-12.
https://search.emarefa.net/detail/BIM-498125
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Barioni, Eric Diego& Santin, José Roberto& Machado, Isabel Daufenback& Rodrigues, Stephen Fernandes de Paula& Ferraz-de-Paula, Viviane& Wagner, Theodoro Marcel…[et al.]. Achyrocline satureioides (Lam.) D.C. Hydroalcoholic Extract Inhibits Neutrophil Functions Related to Innate Host Defense. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-498125
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-498125
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)