Physical Activity and Telomere Biology : Exploring the Link with Aging-Related Disease Prevention
المؤلفون المشاركون
Roth, Stephen M.
Ludlow, Andrew T.
المصدر
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-02-21
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
العلوم الطبية والصيدلة والعلوم الصحية
الملخص EN
Physical activity is associated with reduced risk of several age-related diseases as well as with increased longevity in both rodents and humans.
Though these associations are well established, evidence of the molecular and cellular factors associated with reduced disease risk and increased longevity resulting from physical activity is sparse.
A long-standing hypothesis of aging is the telomere hypothesis: as a cell divides, telomeres shorten resulting eventually in replicative senescence and an aged phenotype.
Several reports have recently associated telomeres and telomere-related proteins to diseases associated with physical inactivity and aging including cardiovascular disease, insulin resistance, and hypertension.
Interestingly several reports have also shown that longer telomeres are associated with higher physical activity levels, indicating a potential mechanistic link between physical activity, reduced age-related disease risk, and longevity.
The primary purpose of this review is to discuss the potential importance of physical activity in telomere biology in the context of inactivity- and age-related diseases.
A secondary purpose is to explore potential mechanisms and important avenues for future research in the field of telomeres and diseases associated with physical inactivity and aging.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ludlow, Andrew T.& Roth, Stephen M.. 2011. Physical Activity and Telomere Biology : Exploring the Link with Aging-Related Disease Prevention. Journal of Aging Research،Vol. 2011, no. 2011, pp.1-12.
https://search.emarefa.net/detail/BIM-498286
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ludlow, Andrew T.& Roth, Stephen M.. Physical Activity and Telomere Biology : Exploring the Link with Aging-Related Disease Prevention. Journal of Aging Research No. 2011 (2011), pp.1-12.
https://search.emarefa.net/detail/BIM-498286
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ludlow, Andrew T.& Roth, Stephen M.. Physical Activity and Telomere Biology : Exploring the Link with Aging-Related Disease Prevention. Journal of Aging Research. 2011. Vol. 2011, no. 2011, pp.1-12.
https://search.emarefa.net/detail/BIM-498286
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-498286
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر