A Normal Range of KL-6MUC1 Independent of Elevated SP-D Indicates a Better Prognosis in the Patients with Honeycombing on High-Resolution Computed Tomography
المؤلفون المشاركون
Ebina, Masahito
Chiba, Shigeki
Ohta, Hiromitsu
Hisata, Shu
Ono, Shuichi
Nukiwa, Toshihiro
Kimura, Yuichiro
Kobayashi, Takao
Shibata, Naoko
المصدر
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2010-12-28
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Both SP-D and KL-6/MUC1 are established biomarkers of the interstitial pneumonias, including idiopathic pulmonary fibrosis (IPF), but the causes and clinical outcomes based on their independent effects are not known.
Eleven asymptomatic patients, detected with honeycombing on high-resolution computed tomography (HRCT), were compared with 17 other IPF outpatients having slight respiratory symptoms and honeycombing as well.
Although SP-D was increased in both groups, KL-6 was significantly higher in the symptomatic IPF group.
When the patients (n=11) having both biomarkers elevated were compared with the other patients (n=6) with only SP-D elevated, the distribution of fibrotic lesions with honeycombing on HRCT was larger and the survival time was shorter in the patients having both biomarkers elevated.
Immunohistochemical analysis also differentiated these biomarkers in the lung.
These results suggest both a cause and the prognostic value of dissociation of these biomarkers.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hisata, Shu& Kimura, Yuichiro& Shibata, Naoko& Ono, Shuichi& Kobayashi, Takao& Chiba, Shigeki…[et al.]. 2010. A Normal Range of KL-6MUC1 Independent of Elevated SP-D Indicates a Better Prognosis in the Patients with Honeycombing on High-Resolution Computed Tomography. Pulmonary Medicine،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-499516
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hisata, Shu…[et al.]. A Normal Range of KL-6MUC1 Independent of Elevated SP-D Indicates a Better Prognosis in the Patients with Honeycombing on High-Resolution Computed Tomography. Pulmonary Medicine No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-499516
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hisata, Shu& Kimura, Yuichiro& Shibata, Naoko& Ono, Shuichi& Kobayashi, Takao& Chiba, Shigeki…[et al.]. A Normal Range of KL-6MUC1 Independent of Elevated SP-D Indicates a Better Prognosis in the Patients with Honeycombing on High-Resolution Computed Tomography. Pulmonary Medicine. 2010. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-499516
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-499516
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر