Cyclooxygenase Inhibitor Associated with Carboplatin in Treatment of Metastatic Nasal Carcinoma in Dog
المؤلفون المشاركون
Gouveia Calazans, Sabryna
Fonseca-Alves, Carlos Eduardo
Gonçalves Corrêa, Aline
Elias, Fabiana
المصدر
Journal of Applied Mathematics
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-02-12
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
A 10-year-old, intact male, pinscher was presented with unilateral bloodstained nasal discharge, sneezing, dyspnea, zygomatic arch deformity, submandibular lymph node increase, blindness in right eye, and exophthalmia.
After clinical examination, it was found that the animal presented with upper respiratory tract dyspnea origin, possibly caused by an obstructive process.
Complete blood count (CBC), ocular ultrasonography, thoracic radiographs, mandibular lymph node, and nasal sinus fine needle aspiration were performed.
The right mandibular lymph node excisional biopsy was conducted and a tumor sample was obtained through the nasal fistula at hard palate.
The material was processed, paraffin embedded, sectioned, and stained with hematoxylin and eosin.
Immunohistochemical staining for cytokeratin (AE1/AE3), vimentin, and COX-2 was performed.
After histopathological evaluation nasal carcinoma diagnosis was obtained.
Chemotherapy was established with carboplatin 300 mg/m2 intravenously—four cycles with intervals of 21 days—and firocoxib 5 mg/kg orally every 24 hours for 7 months.
After 7 months the treatment started, the animal presented with ataxia, vocalization, hyperesthesia, and anorexia.
Due the clinical condition presented, the animal owner opted for performing euthanasia.
The chemotherapy protocol was effective causing the disease stagnation, minimizing the clinical signs, and extending patient survival and quality of life.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Fonseca-Alves, Carlos Eduardo& Gonçalves Corrêa, Aline& Elias, Fabiana& Gouveia Calazans, Sabryna. 2014. Cyclooxygenase Inhibitor Associated with Carboplatin in Treatment of Metastatic Nasal Carcinoma in Dog. Journal of Applied Mathematics،Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-500535
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Fonseca-Alves, Carlos Eduardo…[et al.]. Cyclooxygenase Inhibitor Associated with Carboplatin in Treatment of Metastatic Nasal Carcinoma in Dog. Journal of Applied Mathematics No. 2014 (2014), pp.1-4.
https://search.emarefa.net/detail/BIM-500535
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Fonseca-Alves, Carlos Eduardo& Gonçalves Corrêa, Aline& Elias, Fabiana& Gouveia Calazans, Sabryna. Cyclooxygenase Inhibitor Associated with Carboplatin in Treatment of Metastatic Nasal Carcinoma in Dog. Journal of Applied Mathematics. 2014. Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-500535
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-500535
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر