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An Association between Bevacizumab and Recurrent Posterior Reversible Encephalopathy Syndrome in a Patient Presenting with Deep Vein Thrombosis : A Case Report and Review of the Literature
المؤلفون المشاركون
Lazarus, Mark
Amundson, Stanley
Belani, Rajesh
المصدر
Case Reports in Oncological Medicine
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-11-29
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
Background.
The posterior reversible encephalopathy syndrome (PRES) is a syndrome characterized by hypertension, headache, seizures, and visual disturbances.
Causes of PRES include preeclampsia/eclampsia, hypertension, and recently bevacizumab, a monoclonal antibody vascular endothelial growth factor (VEGF) inhibitor.
There is no information to date about PRES recurrence in patients taking bevacizumab or descriptions of deep vein thrombosis (DVT) in the setting of PRES.
We reviewed data on a patient receiving bevacizumab who presented with a DVT and PRES and later developed recurrent PRES.
Case.
A 72-year-old man with metastatic pulmonary adenocarcinoma received maintenance bevacizumab following six cycles of carboplatin and paclitaxel.
Following his eighth dose of bevacizumab, he developed a DVT as well as PRES.
He made a rapid recovery and was discharged from the hospital but went on to develop PRES recurrence nine days following his original episode.
Conclusion.
Several mechanisms exist whereby exposure to bevacizumab could be related to the development of both DVT and PRES by inducing global endothelial dysfunction.
Recurrent PRES may result from bevacizumab’s prolonged half-life (11–50 days) and suboptimal blood pressure control.
In the setting of bevacizumab, PRES surveillance may play a similar role in preeclampsia screening as both diseases share similar antiangiogenic signaling pathways.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Lazarus, Mark& Amundson, Stanley& Belani, Rajesh. 2012. An Association between Bevacizumab and Recurrent Posterior Reversible Encephalopathy Syndrome in a Patient Presenting with Deep Vein Thrombosis : A Case Report and Review of the Literature. Case Reports in Oncological Medicine،Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-500682
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Lazarus, Mark…[et al.]. An Association between Bevacizumab and Recurrent Posterior Reversible Encephalopathy Syndrome in a Patient Presenting with Deep Vein Thrombosis : A Case Report and Review of the Literature. Case Reports in Oncological Medicine No. 2012 (2012), pp.1-4.
https://search.emarefa.net/detail/BIM-500682
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Lazarus, Mark& Amundson, Stanley& Belani, Rajesh. An Association between Bevacizumab and Recurrent Posterior Reversible Encephalopathy Syndrome in a Patient Presenting with Deep Vein Thrombosis : A Case Report and Review of the Literature. Case Reports in Oncological Medicine. 2012. Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-500682
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-500682
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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