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Radiation Therapy in Addition to Gross Total Resection of Retroperitoneal Sarcoma Results in Prolonged Survival : Results from a Single Institutional Study
المؤلفون المشاركون
Kinsella, Timothy J.
Zagar, Timothy M.
Kim, Julian A.
Chen, William C.
Kunos, Charles A.
Shenk, Robert R.
Abdul-Karim, Fadi W.
Seo, Yuji
Harpp, Deb
المصدر
العدد
المجلد 2008، العدد 2008 (31 ديسمبر/كانون الأول 2008)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2009-01-29
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Purpose.
Typical treatment of retroperitoneal sarcomas (RPSs) is surgery with or without radiation therapy for localized disease.
With surgery alone, local failure rates are as high as 90%; this led to radiation therapy playing an important role in the treatment of RPSs.
Methods.
Thirty-one patients with retroperitoneal sarcoma treated with gross total resection and radiation therapy make up this retrospective analysis.
Nineteen were treated preoperatively and 12 postoperatively (median dose, 59.4 Gy)—sixteen also received intraoperative radiation therapy (IORT) (median dose, 11 Gy).
Patients were followed with stringent regimens, including frequent CT scans of the chest, abdomen, and pelvis.
Results.
With a median follow-up of 19 months (range 1–66 months), the 2-year overall survival (OS) rate is 70% (median, 52 months).
The 2-year locoregional control (LRC) rate is 77% (median, 61.6 months).
The 2-year distant disease free survival (DDFS) rate is 70% (median not reached).
There were no differences in radiation-related acute and late toxicities among patients treated pre- versus postoperatively, whether with or without IORT.
Conclusions.
Compared to surgery alone, neoadjuvant or adjuvant radiation therapy offers patients with RPS an excellent chance for long-term LRC, DDS, and OS.
The integration of modern treatment planning for external beam radiation therapy and IORT allows for higher doses to be delivered with acceptable toxicities.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zagar, Timothy M.& Shenk, Robert R.& Kim, Julian A.& Harpp, Deb& Kunos, Charles A.& Abdul-Karim, Fadi W.…[et al.]. 2009. Radiation Therapy in Addition to Gross Total Resection of Retroperitoneal Sarcoma Results in Prolonged Survival : Results from a Single Institutional Study. Journal of Oncology،Vol. 2008, no. 2008, pp.1-11.
https://search.emarefa.net/detail/BIM-501019
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zagar, Timothy M.…[et al.]. Radiation Therapy in Addition to Gross Total Resection of Retroperitoneal Sarcoma Results in Prolonged Survival : Results from a Single Institutional Study. Journal of Oncology No. 2008 (2008), pp.1-11.
https://search.emarefa.net/detail/BIM-501019
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zagar, Timothy M.& Shenk, Robert R.& Kim, Julian A.& Harpp, Deb& Kunos, Charles A.& Abdul-Karim, Fadi W.…[et al.]. Radiation Therapy in Addition to Gross Total Resection of Retroperitoneal Sarcoma Results in Prolonged Survival : Results from a Single Institutional Study. Journal of Oncology. 2009. Vol. 2008, no. 2008, pp.1-11.
https://search.emarefa.net/detail/BIM-501019
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-501019
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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