Effect of Korean Herbal Medicine Combined with a Probiotic Mixture on Diarrhea-Dominant Irritable Bowel Syndrome : A Double-Blind, Randomized, Placebo-Controlled Trial
المؤلفون المشاركون
Chung, Won-Seok
Park, Jae-Woo
Kim, Seul-Ki
Lee, Beom-Joon
Ryu, Bongha
Seo, Jae-gu
Kim, Jinsung
Lee, Jin-Moo
Han, Gajin
Yeo, Inkwon
Ko, Seok-Jae
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-12-05
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Introduction.
Although combination therapy with herbal medicine and probiotics is gaining popularity for controlling diarrhea-dominant irritable bowel syndrome (D-IBS) symptoms, few studies have investigated its clinical effects.
Materials and Methods.
Fifty-three patients with D-IBS were randomly allocated into 1 of the following 4 groups: herbal medicine (Gwakhyangjeonggisan; GJS) plus probiotics (Duolac7S; DUO), GJS plus placebo DUO, placebo GJS plus DUO, and placebo GJS plus placebo DUO.
The study period consisted of a 2-week run-in, 8 weeks of administration, and 2 weeks of follow-up.
The primary outcomes were weekly adequate relief (AR) of overall IBS symptoms and the proportion of responders (PR) during the administration period.
The secondary outcomes included individual IBS symptoms, stool assessment, and quality of life.
Changes of intestinal microbiota and intestinal permeability were also analyzed.
Results and Discussion.
Weekly AR was not different among the 4 groups throughout the treatment period.
However, the 3 treatment groups exhibited significant improvements in PR compared to the findings in the placebo group.
In the intestinal microbiota assessment, herbal medicine and probiotics synergistically increased beneficial bacteria counts.
Conclusion.
Combination therapy with herbal medicine and probiotics appears to relieve overall IBS symptoms by synergistically increasing beneficial intestinal microbe counts.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ko, Seok-Jae& Han, Gajin& Kim, Seul-Ki& Seo, Jae-gu& Chung, Won-Seok& Ryu, Bongha…[et al.]. 2013. Effect of Korean Herbal Medicine Combined with a Probiotic Mixture on Diarrhea-Dominant Irritable Bowel Syndrome : A Double-Blind, Randomized, Placebo-Controlled Trial. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-501067
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ko, Seok-Jae…[et al.]. Effect of Korean Herbal Medicine Combined with a Probiotic Mixture on Diarrhea-Dominant Irritable Bowel Syndrome : A Double-Blind, Randomized, Placebo-Controlled Trial. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-10.
https://search.emarefa.net/detail/BIM-501067
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ko, Seok-Jae& Han, Gajin& Kim, Seul-Ki& Seo, Jae-gu& Chung, Won-Seok& Ryu, Bongha…[et al.]. Effect of Korean Herbal Medicine Combined with a Probiotic Mixture on Diarrhea-Dominant Irritable Bowel Syndrome : A Double-Blind, Randomized, Placebo-Controlled Trial. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-501067
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-501067
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر