Sarcopenic Obesity and Cognitive Functioning : The Mediating Roles of Insulin Resistance and Inflammation?
المؤلفون المشاركون
Levine, M. E.
Crimmins, Eileen M.
المصدر
Current Gerontology and Geriatrics Research
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-05-07
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
This study examined the influence of insulin resistance and inflammation on the association between body composition and cognitive performance in older adults, aged 60–69 and aged 70 and older.
Subjects included 1127 adults from NHANES 1999–2002.
Body composition was categorized based on measurements of muscle mass and waist circumference as sarcopenic nonobese, nonsarcopenic obese, sarcopenic obese, and normal.
Using OLS regression models, our findings suggest body composition is not associated with cognitive functioning in adults ages 60–69; however, for adults aged 70 and over, sarcopenia and obesity, either independently or concurrently, were associated with worse cognitive functioning relative to non-sarcopenic non-obese older adults.
Furthermore, insulin resistance accounted for a significant proportion of the relationship between cognitive performance and obesity, with or without sarcopenia.
Additionally, although high CRP was significantly associated with poorer cognitive functioning in adults ages 60–69, it did not influence the association between body composition and cognitive performance.
This study provides evidence that age-related physiological maladaptations, such as metabolic deregulation, which are associated with abdominal fat, may simultaneously contribute to lower cognition and muscle mass, reflecting a degradation of multiple physiological systems.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Levine, M. E.& Crimmins, Eileen M.. 2012. Sarcopenic Obesity and Cognitive Functioning : The Mediating Roles of Insulin Resistance and Inflammation?. Current Gerontology and Geriatrics Research،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-501224
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Levine, M. E.& Crimmins, Eileen M.. Sarcopenic Obesity and Cognitive Functioning : The Mediating Roles of Insulin Resistance and Inflammation?. Current Gerontology and Geriatrics Research No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-501224
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Levine, M. E.& Crimmins, Eileen M.. Sarcopenic Obesity and Cognitive Functioning : The Mediating Roles of Insulin Resistance and Inflammation?. Current Gerontology and Geriatrics Research. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-501224
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-501224
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر