![](/images/graphics-bg.png)
Weight Loss and Melatonin Reduce Obesity-Induced Oxidative Damage in Rat Testis
المؤلفون المشاركون
Erdemir, Fikret
Uluocak, Nihat
Atılgan, Doğan
Markoc, Fatma
Parlaktas, Bekir Suha
Ozyurt, Huseyin
Erkorkmaz, Unal
Kilic, Sahin
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-09-08
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Aim.
We aimed to evaluate the antioxidant effects of weight loss and melatonin on the obesity-induced oxidative damage in rat testes.
Materials and Methods.
28 male Wistar albino rats were randomly divided into 4 groups, each consisting of 7 rats: control group (Group 1), obesity group (Group 2), obesity + MLT group (Group 3), and weight loss group (Group 4).
Rats were weighed at the beginning and at the end of the study.
Bilateral orchiectomy was performed and 5 cc blood samples were obtained from all of the rats.
Superoxide dismutase (SOD), malondialdehyde (MDA), and protein carbonyl (PC) levels were analysed in the testicular tissues and serum.
Spermatogenesis was evaluated with the Johnsen scoring system.
Results.
The testicular tissue and serum levels of MDA, PC, and SOD activity were increased in the obesity group in comparison to the sham operated group (P<0.05).
Weight loss and melatonin treatment ameliorated MDA, PC, and SOD levels in testicular tissue and serum significantly (P<0.05).
There was no significant difference between groups in terms of mean Johnsen score (P=0.727).
Conclusion.
Experimentally created obesity caused oxidative stress and both melatonin and weight loss reduced oxidative stress parameters in rat testes.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Atılgan, Doğan& Parlaktas, Bekir Suha& Uluocak, Nihat& Erdemir, Fikret& Kilic, Sahin& Erkorkmaz, Unal…[et al.]. 2013. Weight Loss and Melatonin Reduce Obesity-Induced Oxidative Damage in Rat Testis. Advances in Urology،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-501988
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Atılgan, Doğan…[et al.]. Weight Loss and Melatonin Reduce Obesity-Induced Oxidative Damage in Rat Testis. Advances in Urology No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-501988
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Atılgan, Doğan& Parlaktas, Bekir Suha& Uluocak, Nihat& Erdemir, Fikret& Kilic, Sahin& Erkorkmaz, Unal…[et al.]. Weight Loss and Melatonin Reduce Obesity-Induced Oxidative Damage in Rat Testis. Advances in Urology. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-501988
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-501988
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)