A Metabolomics-Based Strategy for the Quality Control of Traditional Chinese Medicine : Shengmai Injection as a Case Study
المؤلفون المشاركون
Xie, Guoxiang
Jia, Wei
Chen, Huiyuan
Li, Xiaodong
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-01-20
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Quality control of traditional Chinese medicines (TCMs) used clinically is becoming a challenge and has limited the development of TCM due to the high variability in concentration levels of active ingredients and markers as well as the lack of well-established criteria.
Using Shengmai injection, which is a well-established TCM, as an example, we developed an integrated profiling approach that simultaneously captures the entire spectrum of ingredients and quantitatively determines the levels of seven key ingredients in the TCM product.
A multivariate statistical model was constructed to establish a “seven-marker-” based quality standard that qualified the majority of samples in this study.
This newly developed strategy showed that a panel of key ingredients or markers in the TCM product were relatively consistent within a statistically acceptable range.
Therefore, this metabolomics-based approach will complement the current quality control standard using the concentration of several key ingredients or their total content and help improve the consistency and clinic efficacy of TCM products.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Li, Xiaodong& Chen, Huiyuan& Jia, Wei& Xie, Guoxiang. 2013. A Metabolomics-Based Strategy for the Quality Control of Traditional Chinese Medicine : Shengmai Injection as a Case Study. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-501995
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Li, Xiaodong…[et al.]. A Metabolomics-Based Strategy for the Quality Control of Traditional Chinese Medicine : Shengmai Injection as a Case Study. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-501995
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Li, Xiaodong& Chen, Huiyuan& Jia, Wei& Xie, Guoxiang. A Metabolomics-Based Strategy for the Quality Control of Traditional Chinese Medicine : Shengmai Injection as a Case Study. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-501995
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-501995
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر