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Immunotherapy Responsive Autoimmune Subacute Encephalitis : A Report of Two Cases
المؤلفون المشاركون
Lynch, Sharon G.
Mittal, Manoj
Hammond, Nancy
المصدر
العدد
المجلد 2010، العدد 2010 (31 ديسمبر/كانون الأول 2010)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2010-03-18
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
Objective.
To describe the clinical characteristics and radiological findings in two patients with subacute encephalitis associated with elevated serum voltage-gated potassium channel antibody (VGKCAb) and antithyroperoxidase (TPO) antibody.
Case Reports.
Case 1: 63-year-old woman was admitted for altered mental status and possible seizure activity.
MRI brain showed hyperintensity in the bilateral hippocampal areas.
She was positive for VGKCAb and anti-TPO antibodies.
She was treated with steroids, IVIG, plasma exchange and azathioprine.
After 8 months, she had marked improvement in her memory and seizures.
Case 2: 61-year-old woman was admitted for video EEG monitoring of unclassified seizure and cognitive function decline.
MRI of the brain showed mild hyperintensity in bilateral hippocampal areas and significant atrophy in the frontotemporal lesion.
Anti-TPO antibody and VGKCAb were positive.
She was treated with steroids, plasma exchange and azathioprine.
After 9 months, she had marked improvement in her memory and seizures.
Conclusion.
Autoimmune subacute encephalitis appears to be an underdiagnosed entity.
It is important to screen patients with subacute encephalitis for anti-TPO antibody and VGKCAb, particularly in the presence of seizures.
Immunosuppressive therapy appears to be effective in treating this entity.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Mittal, Manoj& Hammond, Nancy& Lynch, Sharon G.. 2010. Immunotherapy Responsive Autoimmune Subacute Encephalitis : A Report of Two Cases. Case Reports in Medicine،Vol. 2010, no. 2010, pp.1-4.
https://search.emarefa.net/detail/BIM-502104
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Mittal, Manoj…[et al.]. Immunotherapy Responsive Autoimmune Subacute Encephalitis : A Report of Two Cases. Case Reports in Medicine No. 2010 (2010), pp.1-4.
https://search.emarefa.net/detail/BIM-502104
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Mittal, Manoj& Hammond, Nancy& Lynch, Sharon G.. Immunotherapy Responsive Autoimmune Subacute Encephalitis : A Report of Two Cases. Case Reports in Medicine. 2010. Vol. 2010, no. 2010, pp.1-4.
https://search.emarefa.net/detail/BIM-502104
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-502104
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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