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dTGS : Method for Effective Components Identification from Traditional Chinese Medicine Formula and Mechanism Analysis
المؤلفون المشاركون
Wu, Yi
Ren, Yinglong
Wang, Yun
Gu, Hao
Luo, Ji
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-12-18
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Because of the complexity of the components in Traditional Chinese Medicine formula (TCM formula), it is still a challenge to identify its effective components, to elucidate the mechanism of the components, and to discover the relationship between components and therapy objectives.
In this paper, a method called directed TCM grammar systems (dTGS) for effective component identification was proposed using entity grammar systems (EGS) as the theoretical framework.
The component-disease relationship of a TCM formula (i.e., Bai-Hu decoction plus Wasting-Thirsting formula, BHDWT) and one disease (i.e., type 2 diabetes mellitus) treated with it was studied, and the effective component groups (ECGs) were identified.
19 compounds were found acting on 20 proteins in type 2 diabetes mellitus (T2D) disease network, and 15 compounds were determined as the candidate effective components.
Results indicated that this method can be used to identify the effective components and provide an innovative way to elucidate the molecular mechanism of TCM formulas.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Luo, Ji& Ren, Yinglong& Gu, Hao& Wu, Yi& Wang, Yun. 2013. dTGS : Method for Effective Components Identification from Traditional Chinese Medicine Formula and Mechanism Analysis. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-502392
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Luo, Ji…[et al.]. dTGS : Method for Effective Components Identification from Traditional Chinese Medicine Formula and Mechanism Analysis. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-502392
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Luo, Ji& Ren, Yinglong& Gu, Hao& Wu, Yi& Wang, Yun. dTGS : Method for Effective Components Identification from Traditional Chinese Medicine Formula and Mechanism Analysis. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-502392
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-502392
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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