Iodine Content and Distribution in Thyroid Specimens from Two Patients with Graves' Disease Pretreated with Either Propylthiouracil or Stable Iodine : Analysis Using X-Ray Fluorescence and Time-of-Flight Secondary Ion Mass Spectrometry
المؤلفون المشاركون
Filipsson Nyström, Helena
Lausmaa, Jukka
Jansson, Svante
Berg, Gertrud
Hansson, Marie
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-02-09
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Patients with Graves' disease can be medically prepared before surgery in different ways, which may have various effects on iodine stores.
Thyroid specimens were collected at surgery from two patients pretreated with propylthiouracil (PTU) and stable iodine, respectively.
A quantitative analysis of iodine content was performed using X-ray fluorescence (XRF) in frozen tissue and a qualitative analysis of aldehyde-fixed material with Time-of-Flight Secondary Ion Mass Spectrometry (TOF-SIMS).
Iodine concentrations were 0.9 mg/mL and 0.5 mg/mL in the thyroid tissue from the patients treated with PTU and stable iodine respectively.
TOF-SIMS showed iodine in the follicle lumina in both.
However, in the PTU case, iodine was also seen within the thyrocytes indicating accumulation of iodinated compounds from uninhibited hormone release.
XRF and TOF-SIMS can be used to follow iodine distribution within the thyroid and the intricate processes following the different medical treatment alternatives in Graves' disease.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hansson, Marie& Filipsson Nyström, Helena& Jansson, Svante& Lausmaa, Jukka& Berg, Gertrud. 2012. Iodine Content and Distribution in Thyroid Specimens from Two Patients with Graves' Disease Pretreated with Either Propylthiouracil or Stable Iodine : Analysis Using X-Ray Fluorescence and Time-of-Flight Secondary Ion Mass Spectrometry. Case Reports in Endocrinology،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-502581
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hansson, Marie…[et al.]. Iodine Content and Distribution in Thyroid Specimens from Two Patients with Graves' Disease Pretreated with Either Propylthiouracil or Stable Iodine : Analysis Using X-Ray Fluorescence and Time-of-Flight Secondary Ion Mass Spectrometry. Case Reports in Endocrinology No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-502581
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hansson, Marie& Filipsson Nyström, Helena& Jansson, Svante& Lausmaa, Jukka& Berg, Gertrud. Iodine Content and Distribution in Thyroid Specimens from Two Patients with Graves' Disease Pretreated with Either Propylthiouracil or Stable Iodine : Analysis Using X-Ray Fluorescence and Time-of-Flight Secondary Ion Mass Spectrometry. Case Reports in Endocrinology. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-502581
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-502581
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر