Vitamins E and C Alleviate the Germ Cell Loss and Oxidative Stress in Cryptorchidism When Administered Separately but Not When Combined in Rats
المؤلفون المشاركون
Afolabi, Ayobami Oladele
Alagbonsi, Isiaka Abdullateef
Olotu, Olaolu Opeyemi
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-10-30
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
العلوم الطبية والصيدلة والعلوم الصحية
علم الصيدلة
الملخص EN
The antioxidant effects of vitamins C and E on cryptorchidism-induced oxidative stress were investigated in male Sprague-Dawley rats.
Forty rats (200–250 g) were randomly divided in a blinded fashion into five groups (n=8).
Group 1 was sham operated and treated with vehicle (corn-oil, 10 mL/kg).
Groups 2, 3, 4, and 5 were rendered unilaterally cryptorchid and treated with vehicle (10 mL/kg), vitamin E solution (75 mg/kg), vitamin C solution (1.25 g/kg), and combination of vitamin E (75 mg/kg) and vitamin C (1.25 g/kg) solutions, respectively.
Germ cell count, superoxide dismutase (SOD), total protein (TP), and testicular weight (TW) were lower, but malondialdhyde (MDA) was higher in the cryptorchid rats than the sham-operated rats.
When administered separately, vitamins C and E increased germ cell count, SOD, TP, and TW but did not reduce MDA in the cryptorchid rats when compared to the vehicle-treated cryptorchid rats.
However, there was no significant difference in these parameters between vehicle-treated and combined vitamins C- and E-treated rats.
This suggests that vitamins E and C alleviate the germ cell loss and oxidative stress in cryptorchidism when administered separately but not when combined in rats.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Afolabi, Ayobami Oladele& Olotu, Olaolu Opeyemi& Alagbonsi, Isiaka Abdullateef. 2012. Vitamins E and C Alleviate the Germ Cell Loss and Oxidative Stress in Cryptorchidism When Administered Separately but Not When Combined in Rats. ISRN Pharmacology،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-502725
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Afolabi, Ayobami Oladele…[et al.]. Vitamins E and C Alleviate the Germ Cell Loss and Oxidative Stress in Cryptorchidism When Administered Separately but Not When Combined in Rats. ISRN Pharmacology No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-502725
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Afolabi, Ayobami Oladele& Olotu, Olaolu Opeyemi& Alagbonsi, Isiaka Abdullateef. Vitamins E and C Alleviate the Germ Cell Loss and Oxidative Stress in Cryptorchidism When Administered Separately but Not When Combined in Rats. ISRN Pharmacology. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-502725
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-502725
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر