HIV Assembly and Budding : Ca2+ Signaling and Non-ESCRT Proteins Set the Stage

المؤلفون المشاركون

Carter, Carol A.
Ehrlich, Lorna S.

المصدر

Molecular Biology International

العدد

المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-12، 12ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2012-06-12

دولة النشر

مصر

عدد الصفحات

12

التخصصات الرئيسية

العلوم الطبيعية والحياتية (متداخلة التخصصات)
الأحياء

الملخص EN

More than a decade has elapsed since the link between the endosomal sorting complex required for transport (ESCRT) machinery and HIV-1 protein trafficking and budding was first identified.

L domains in HIV-1 Gag mediate recruitment of ESCRT which function in bud abscission releasing the viral particle from the host cell.

Beyond virus budding, the ESCRT machinery is also involved in the endocytic pathway, cytokinesis, and autophagy.

In the past few years, the number of non-ESCRT host proteins shown to be required in the assembly process has also grown.

In this paper, we highlight the role of recently identified cellular factors that link ESCRT machinery to calcium signaling machinery and we suggest that this liaison contributes to setting the stage for productive ESCRT recruitment and mediation of abscission.

Parallel paradigms for non-ESCRT roles in virus budding and cytokinesis will be discussed.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Ehrlich, Lorna S.& Carter, Carol A.. 2012. HIV Assembly and Budding : Ca2+ Signaling and Non-ESCRT Proteins Set the Stage. Molecular Biology International،Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-503333

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Ehrlich, Lorna S.& Carter, Carol A.. HIV Assembly and Budding : Ca2+ Signaling and Non-ESCRT Proteins Set the Stage. Molecular Biology International No. 2012 (2012), pp.1-12.
https://search.emarefa.net/detail/BIM-503333

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Ehrlich, Lorna S.& Carter, Carol A.. HIV Assembly and Budding : Ca2+ Signaling and Non-ESCRT Proteins Set the Stage. Molecular Biology International. 2012. Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-503333

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-503333