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The Effect of Negative Poisson’s Ratio Polyurethane Scaffolds for Articular Cartilage Tissue Engineering Applications
المؤلفون المشاركون
المصدر
Advances in Materials Science and Engineering
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-10-02
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
العلوم الهندسية و تكنولوجيا المعلومات
الملخص EN
An auxetic polyurethane (PU) scaffold was prepared to investigate chondrocyte proliferation under compressive stimulation for cartilage regeneration.
To give a negative Poisson’s ratio to the PU scaffold, volumetric compression with a 3 : 1 ratio was applied during heat treatment.
For the control PU scaffold, the Poisson’s ratio was 0.9 ± 0.25 with elongation at 20% of the strain range.
Poisson’s ratio for experimental specimens was approximately −0.4 ± 0.12 under the same conditions.
In cell proliferation tests, cells were cultivated within the prepared scaffold under compression with a 20% strain range.
With a 20% strain range elongation, the compressive load was approximately 0.3 N.
The experimental group showed a 1.3 times higher cellular proliferation rate than that of the control group after 3 days in culture.
At day 5 of culture, however, the rate of proliferation of the control group increased so that there was no significant difference between groups.
However, collagen content (produced by the cells) in the cell-proliferated medium was 1.5 times higher in the experimental group after 5 days in culture.
This may have been due to the effectiveness of the auxetic structure of the scaffold.
An isotropic compressive load was transmitted to the cells due to the negative Poisson ratio of the scaffold.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Park, Yeong Jun& Kim, Jeong Koo. 2013. The Effect of Negative Poisson’s Ratio Polyurethane Scaffolds for Articular Cartilage Tissue Engineering Applications. Advances in Materials Science and Engineering،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-503498
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Park, Yeong Jun& Kim, Jeong Koo. The Effect of Negative Poisson’s Ratio Polyurethane Scaffolds for Articular Cartilage Tissue Engineering Applications. Advances in Materials Science and Engineering No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-503498
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Park, Yeong Jun& Kim, Jeong Koo. The Effect of Negative Poisson’s Ratio Polyurethane Scaffolds for Articular Cartilage Tissue Engineering Applications. Advances in Materials Science and Engineering. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-503498
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-503498
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