Immunohistochemical Biomarkers in Gastric Cancer Research and Management

المؤلفون المشاركون

Lastraioli, Elena
Raffaella Romoli, Maria
Arcangeli, Annarosa

المصدر

International Journal of Surgical Oncology

العدد

المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-9، 9ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2012-06-24

دولة النشر

مصر

عدد الصفحات

9

التخصصات الرئيسية

الأمراض
الطب البشري

الملخص EN

Gastric cancer still represents a major health problem, despite a decrease in its incidence in the last years.

Due to the social impact of gastric cancer (GC), there is a need for novel biomarkers in order to stratify patients into appropriate screening, surveillance, or treatment programs.

Although histopathology remains the most reliable and less expensive method, numerous efforts have been made searching for novel biomarkers.

In recent years, several molecules have been identified and tested for their clinical relevance in GC management.

In this paper, we will focus on a well-known GC marker, whose determination is mandatory in GC, HER2, a marker whose correlation with prognosis is still controversial (VEGF-A) and a quite novel, unconventional marker, the ether-à-go-go-related gene 1 (hERG1).

All these proteins can be easily detected with immunohistochemistry, a technique widely used both in diagnostic and research laboratories that represents a link between surgical and molecular pathology, basic science, and clinical medicine.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Lastraioli, Elena& Raffaella Romoli, Maria& Arcangeli, Annarosa. 2012. Immunohistochemical Biomarkers in Gastric Cancer Research and Management. International Journal of Surgical Oncology،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-504775

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Lastraioli, Elena…[et al.]. Immunohistochemical Biomarkers in Gastric Cancer Research and Management. International Journal of Surgical Oncology No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-504775

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Lastraioli, Elena& Raffaella Romoli, Maria& Arcangeli, Annarosa. Immunohistochemical Biomarkers in Gastric Cancer Research and Management. International Journal of Surgical Oncology. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-504775

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-504775