Immunohistochemical Biomarkers in Gastric Cancer Research and Management
Joint Authors
Lastraioli, Elena
Raffaella Romoli, Maria
Arcangeli, Annarosa
Source
International Journal of Surgical Oncology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-06-24
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Gastric cancer still represents a major health problem, despite a decrease in its incidence in the last years.
Due to the social impact of gastric cancer (GC), there is a need for novel biomarkers in order to stratify patients into appropriate screening, surveillance, or treatment programs.
Although histopathology remains the most reliable and less expensive method, numerous efforts have been made searching for novel biomarkers.
In recent years, several molecules have been identified and tested for their clinical relevance in GC management.
In this paper, we will focus on a well-known GC marker, whose determination is mandatory in GC, HER2, a marker whose correlation with prognosis is still controversial (VEGF-A) and a quite novel, unconventional marker, the ether-à-go-go-related gene 1 (hERG1).
All these proteins can be easily detected with immunohistochemistry, a technique widely used both in diagnostic and research laboratories that represents a link between surgical and molecular pathology, basic science, and clinical medicine.
American Psychological Association (APA)
Lastraioli, Elena& Raffaella Romoli, Maria& Arcangeli, Annarosa. 2012. Immunohistochemical Biomarkers in Gastric Cancer Research and Management. International Journal of Surgical Oncology،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-504775
Modern Language Association (MLA)
Lastraioli, Elena…[et al.]. Immunohistochemical Biomarkers in Gastric Cancer Research and Management. International Journal of Surgical Oncology No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-504775
American Medical Association (AMA)
Lastraioli, Elena& Raffaella Romoli, Maria& Arcangeli, Annarosa. Immunohistochemical Biomarkers in Gastric Cancer Research and Management. International Journal of Surgical Oncology. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-504775
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-504775