Morphometric Analysis of Connective Tissue Sheaths of Sural Nerve in Diabetic and Nondiabetic Patients
المؤلفون المشاركون
Kundalić, Jasen
Ugrenović, Sladjana Z.
Antić, Vladimir
Jovanović, Ivan
Petrović, Vladimir
Stefanović, Natalija
Živković, Vladimir S.
Stojanović, Vesna R.
Kundalić, Braca
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-07-23
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
One of the most common complications of diabetes mellitus is diabetic neuropathy.
It may be provoked by metabolic and/or vascular factors, and depending on duration of disease, various layers of nerve may be affected.
Our aim was to investigate influence of diabetes on the epineurial, perineurial, and endoneurial connective tissue sheaths.
The study included 15 samples of sural nerve divided into three groups: diabetic group, peripheral vascular disease group, and control group.
After morphological analysis, morphometric parameters were determined for each case using ImageJ software.
Compared to the control group, the diabetic cases had significantly higher perineurial index (P<0.05) and endoneurial connective tissue percentage (P<0.01).
The diabetic group showed significantly higher epineurial area (P<0.01), as well as percentage of endoneurial connective tissue (P<0.01), in relation to the peripheral vascular disease group.
It is obvious that hyperglycemia and ischemia present in diabetes lead to substantial changes in connective tissue sheaths of nerve, particularly in peri- and endoneurium.
Perineurial thickening and significant endoneurial fibrosis may impair the balance of endoneurial homeostasis and regenerative ability of the nerve fibers.
Future investigations should focus on studying the components of extracellular matrix of connective tissue sheaths in diabetic nerves.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kundalić, Braca& Ugrenović, Sladjana Z.& Jovanović, Ivan& Stefanović, Natalija& Petrović, Vladimir& Kundalić, Jasen…[et al.]. 2014. Morphometric Analysis of Connective Tissue Sheaths of Sural Nerve in Diabetic and Nondiabetic Patients. BioMed Research International،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-504966
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kundalić, Braca…[et al.]. Morphometric Analysis of Connective Tissue Sheaths of Sural Nerve in Diabetic and Nondiabetic Patients. BioMed Research International No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-504966
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kundalić, Braca& Ugrenović, Sladjana Z.& Jovanović, Ivan& Stefanović, Natalija& Petrović, Vladimir& Kundalić, Jasen…[et al.]. Morphometric Analysis of Connective Tissue Sheaths of Sural Nerve in Diabetic and Nondiabetic Patients. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-504966
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-504966
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر