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Acute Myeloid Leukemia Evolving from JAK 2-Positive Primary Myelofibrosis and Concomitant CD5-Negative Mantle Cell Lymphoma : A Case Report and Review of the Literature
المؤلفون المشاركون
Khedr, Salwa
Mangray, Shamlal
Treaba, Diana O.
Winer, Eric S.
Castillo, Jorge J.
Jackson, Cynthia
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-08-02
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Primary myelofibrosis (formerly known as chronic idiopathic myelofibrosis), has the lowest incidence amongst the chronic myeloproliferative neoplasms and is characterized by a rather short median survival and a risk of progression to acute myeloid leukemia (AML) noted in a small subset of the cases, usually as a terminal event.
As observed with other chronic myeloproliferative neoplasms, the bone marrow biopsy may harbor small lymphoid aggregates, often assumed reactive in nature.
In our paper, we present a 70-year-old Caucasian male who was diagnosed with primary myelofibrosis, and after 8 years of followup and therapy developed an AML.
The small lymphoid aggregates noted in his bone marrow were neoplastic in nature and represented bone marrow involvement by a CD5-negative mantle cell lymphoma (MCL) that presented without any associated lymphadenopathy.
We reviewed the English medical literature to identify a single case report of simultaneous association of AML and a MCL in the bone marrow.
The unusual association presented here suggests an increase in observer awareness to apparently benign lymphoid aggregates in chronic myeloproliferative neoplasms.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Treaba, Diana O.& Khedr, Salwa& Mangray, Shamlal& Jackson, Cynthia& Castillo, Jorge J.& Winer, Eric S.. 2012. Acute Myeloid Leukemia Evolving from JAK 2-Positive Primary Myelofibrosis and Concomitant CD5-Negative Mantle Cell Lymphoma : A Case Report and Review of the Literature. Case Reports in Hematology،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-505348
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Treaba, Diana O.…[et al.]. Acute Myeloid Leukemia Evolving from JAK 2-Positive Primary Myelofibrosis and Concomitant CD5-Negative Mantle Cell Lymphoma : A Case Report and Review of the Literature. Case Reports in Hematology No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-505348
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Treaba, Diana O.& Khedr, Salwa& Mangray, Shamlal& Jackson, Cynthia& Castillo, Jorge J.& Winer, Eric S.. Acute Myeloid Leukemia Evolving from JAK 2-Positive Primary Myelofibrosis and Concomitant CD5-Negative Mantle Cell Lymphoma : A Case Report and Review of the Literature. Case Reports in Hematology. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-505348
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-505348
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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